Yuanyuan Zhang, MSc, RN, School of Nursing, Changzhou University, Changzhou, Jiangsu, China.
Caiyan Ding, MSN, RN, Nursing Teaching and Research Department, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, China. Studying for a doctorate in Faculty of Nursing, Chiang Mai University, Chiang Mai, Thailand.
Gastroenterol Nurs. 2021;44(2):E29-E37. doi: 10.1097/SGA.0000000000000588.
This meta-analysis aimed to evaluate the impact of prepackaged low-residue diet (PLRD) on bowel preparation for colonoscopy. We searched PubMed, Web of Science, EMBASE, and Cochrane Library databases from inception to August 2020. Randomized controlled trials (RCTs) comparing PLRD with clear liquid diet (CLD) or self-prepared LRD were considered for inclusion. The analysis calculated the odds ratio (OR) for the rate of adequate bowel preparation, patient tolerance, willingness to repeat bowel preparation, tolerability of bowel preparation, and overall adverse effects. Five RCTs published between 2006 and 2019 (N = 561) were included in our meta-analysis. Compared with the traditional CLD or self-prepared LRD, PLRD showed significantly higher rates of adequate bowel preparation (OR, 2.16; 95% confidence interval [CI], 1.18-3.98; p = .01), patient tolerance (OR, 1.99; 95% CI, 1.30-3.07; p = .002), and willingness to repeat the bowel preparation (OR, 1.68; 95% CI, 1.05-2.70; p = .03), with no differences in adverse events (OR, 0.93; 95% CI, 0.59-1.46; p = .75). Prepackaged low-residue diet improved bowel preparation quality, patient tolerance, and willingness to repeat bowel preparations. Importantly, PLRD does not increase the incidence of adverse events. This suggests that it is effective and safe to use PLRD for bowel preparation before colonoscopy.
本荟萃分析旨在评估预制低残留饮食（PLRD）对结肠镜检查肠道准备的影响。我们检索了从建库至 2020 年 8 月的 PubMed、Web of Science、EMBASE 和 Cochrane Library 数据库。纳入比较 PLRD 与清亮液体饮食（CLD）或自行准备的 LRD 的随机对照试验（RCT）。分析计算了肠道准备充分率、患者耐受性、重复肠道准备意愿、肠道准备耐受性和总体不良事件的比值比（OR）。我们纳入了 2006 年至 2019 年发表的 5 项 RCT（N = 561）进行荟萃分析。与传统的 CLD 或自行准备的 LRD 相比，PLRD 显示出更高的肠道准备充分率（OR，2.16；95%置信区间[CI]，1.18-3.98；p =.01）、患者耐受性（OR，1.99；95% CI，1.30-3.07；p =.002）和重复肠道准备的意愿（OR，1.68；95% CI，1.05-2.70；p =.03），不良事件发生率无差异（OR，0.93；95% CI，0.59-1.46；p =.75）。预制低残留饮食可改善肠道准备质量、患者耐受性和重复肠道准备的意愿。重要的是，PLRD 不会增加不良事件的发生率。这表明 PLRD 用于结肠镜检查前肠道准备是有效且安全的。
