Willekens Barbara, Kleffner Ilka
Department of Neurology, Antwerp University Hospital, Drie Eikenstraat 655, Edegem, 2650, Belgium.
University Hospital Knappschaftskrankenhaus Bochum, Ruhr University Bochum, Bochum, Germany.
Ther Adv Neurol Disord. 2021 Jan 30;14:1756286420981352. doi: 10.1177/1756286420981352. eCollection 2021.
Susac syndrome (SuS) is a rare autoimmune endotheliopathy leading to hearing loss, branch retinal artery occlusions and encephalopathy. Young females are more frequently affected than males, making counselling for family planning an important issue. We reviewed published cases on SuS during pregnancy or in the postpartum period, and selected 27 reports describing the details of 33 patients with SuS. Treatment options and implications for pregnancy and breastfeeding are discussed. We propose new areas for research and suggest a management strategy.
Susac综合征（SuS）是一种罕见的自身免疫性内皮病变，可导致听力丧失、视网膜分支动脉阻塞和脑病。女性比男性更易受影响，因此计划生育咨询成为一个重要问题。我们回顾了孕期或产后Susac综合征的已发表病例，并选取了27篇描述33例Susac综合征患者详细情况的报告。文中讨论了治疗方案以及对妊娠和母乳喂养的影响。我们提出了新的研究领域并建议了一种管理策略。
