International Center for Child Health and Development, Brown School, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Sargent College of Health and Rehabilitation Sciences, Boston University, Boston, MA, 02215, USA.
AIDS Behav. 2021 Nov;25(11):3721-3733. doi: 10.1007/s10461-021-03243-7. Epub 2021 Apr 2.
We assessed the effect of depression, hopelessness, and self-concept on HIV prevention attitudes and knowledge about infection, transmission and sexual risk behavior among adolescents living with HIV in Uganda. Utilizing longitudinal data from 635 adolescents living with HIV, multiple ordinary least square regression was used to evaluate associations between the three indicators of mental health functioning at baseline and HIV knowledge and prevention attitudes at 12-months follow-up. We found that depression (β = - 0.17; 95% CI - 0.31, - 0.04) and hopelessness (β = - 0.16; 95% CI - 0.28, - 0.04) scores at baseline were associated with a 0.17 and 0.16 average reduction in HIV prevention attitudes and HIV knowledge scores, respectively at 12-months follow-up. However, self-concept was not significantly associated with HIV knowledge or prevention attitudes. Adolescents living with HIV with greater levels of hopelessness are at increased risk of having limited HIV knowledge while those with greater symptoms of depression had less favorable HIV prevention attitudes.
我们评估了抑郁、绝望和自我概念对感染、传播和性行为风险的认识以及艾滋病毒预防态度的影响，在乌干达艾滋病毒感染者中，青少年生活。利用来自 635 名艾滋病毒感染者的纵向数据，采用多元普通最小二乘回归分析，评估了基线时心理健康功能的三个指标与 12 个月随访时艾滋病毒知识和预防态度之间的关系。我们发现，基线时的抑郁（β=-0.17；95%置信区间-0.31，-0.04）和绝望（β=-0.16；95%置信区间-0.28，-0.04）评分与 12 个月随访时的艾滋病毒预防态度和艾滋病毒知识评分平均分别降低 0.17 和 0.16 有关。然而，自我概念与艾滋病毒知识或预防态度没有显著关联。绝望程度较高的艾滋病毒感染者可能会有较少的艾滋病毒知识，而抑郁症状较重的患者对艾滋病毒预防的态度不太有利。
