Sudzhaeva S G, Laziuk D G
Kardiologiia. 1988 Mar;28(3):12-6.
A study of 48 coronary patients demonstrated that coronary as well as systemic vasospasm resulting in a drop of propulsive left-ventricular capacity are the principal pathogenic factors leading to myocardial ischemia under emotional stress. In patients with coronary arterial stenosis, increased myocardial oxygen want due to increased stroke and minute volumes contributes significantly to ischemic response to stress. The use of corinfar is advisable to prevent the development of emotion-induced vasospasm. The use of information stress with ECG and central hemodynamic monitoring permits noninvasive diagnosis of coronary spasm.
一项针对48名冠心病患者的研究表明，冠状动脉以及导致左心室推进能力下降的全身性血管痉挛是情绪应激下导致心肌缺血的主要致病因素。在冠状动脉狭窄的患者中，由于每搏输出量和分钟通气量增加导致的心肌需氧量增加，对压力的缺血反应有显著贡献。建议使用氯酯心安来预防情绪诱发的血管痉挛。结合心电图和中心血流动力学监测使用信息应激，可对冠状动脉痉挛进行无创诊断。
