[超极化与乙醇对不同胆碱能受体密度下青蛙终板电流作用的比较]
[Comparison of the action of hyperpolarization and ethanol on frog end-plate currents at different cholinoceptor densities].
作者信息
Giniatullin R A, Khazipov R N, Khamitov Kh S
出版信息
Neirofiziologiia. 1988;20(1):128-30.
PMID:3380206
Abstract
Both hyperpolarization of the postsynaptic membrane and ethanol delayed the decay rate of end-plate currents (EPC) in voltage clamp experiments of frog neuromuscular junctions. After a decrease of the acetylcholine receptors' density by alpha-bungarotoxin, the effect of ethanol, but not that of hyperpolarization, became less pronounced. It is concluded that there are differences between hyperpolarization and ethanol action on the processes controlling the EPC decay rate.
摘要
在蛙神经肌肉接头的电压钳实验中，突触后膜的超极化和乙醇都延缓了终板电流（EPC）的衰减速率。在用α-银环蛇毒素降低乙酰胆碱受体密度后，乙醇的作用变得不那么明显，但超极化的作用并非如此。由此得出结论，超极化和乙醇在控制EPC衰减速率的过程中的作用存在差异。
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