Batjer H H, Devous M D, Purdy P D, Mickey B, Bonte F J, Samson D
Division of Neurological Surgery, University of Texas Health Science Center, Dallas.
Neurosurgery. 1988 May;22(5):913-9.
Regional cerebral blood flow was measured with xenon-133 inhalation single photon emission computed tomography in a patient who developed a neurological deficit after carotid ligation. Hemispheric hypoperfusion was noted in resting studies and impaired vasoreactivity was suggested by lack of symmetrical flow augmentation after acetazolamide administration. Because of progressive neurological deterioration, an extracranial-intracranial bypass was performed. After prompt neurological improvement, repeat cerebral blood flow measurements at 1 and 9 weeks postoperatively confirmed improvement in resting flow and vasoreactivity. It is possible that decreased cerebrovascular reserve implied by measurements of vasoreactivity can identify patients who will benefit from surgical revascularization.
在一名颈动脉结扎后出现神经功能缺损的患者中，采用氙-133吸入单光子发射计算机断层扫描测量局部脑血流量。静息研究中发现半球灌注不足，乙酰唑胺给药后缺乏对称的血流增加提示血管反应性受损。由于神经功能进行性恶化，进行了颅外-颅内搭桥手术。术后迅速出现神经功能改善，术后1周和9周重复进行脑血流量测量，证实静息血流和血管反应性均有改善。血管反应性测量所暗示的脑血管储备减少可能识别出将从手术血运重建中获益的患者。
