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一场新的淘金热:尿路感染当前及正在发展的诊断工具综述

A New Gold Rush: A Review of Current and Developing Diagnostic Tools for Urinary Tract Infections.

作者信息

Xu Raymond, Deebel Nicholas, Casals Randy, Dutta Rahul, Mirzazadeh Majid

机构信息

Wake Forest Baptist Medical Center, Department of Urology, Medical Center Blvd, Winston-Salem, NC 27157, USA.

出版信息

Diagnostics (Basel). 2021 Mar 9;11(3):479. doi: 10.3390/diagnostics11030479.

Abstract

Urinary tract infections (UTIs) are one of the most common infections in the United States and consequently are responsible for significant healthcare expenditure. The standard urine culture is the current gold standard for diagnosing urinary tract infections, however there are limitations of the test that directly contribute to increased healthcare costs. As a result, new and innovative techniques have been developed to address the inefficiencies of the current standard-it remains to be seen whether these tests should be performed adjunctly to, or perhaps even replace the urine culture. This review aims to analyze the advantages and disadvantages of the newer and emerging diagnostic techniques such as PCR, expanded quantitative urine culture (EQUC), and next generation sequencing (NGS).

摘要

尿路感染(UTIs)是美国最常见的感染之一,因此导致了大量的医疗支出。标准尿液培养是目前诊断尿路感染的金标准,然而该检测存在局限性,这直接导致了医疗成本的增加。因此,已经开发了新的创新技术来解决当前标准的低效问题——这些检测是应作为尿液培养的辅助手段进行,还是甚至可能取代尿液培养,还有待观察。本综述旨在分析诸如聚合酶链反应(PCR)、扩展定量尿液培养(EQUC)和下一代测序(NGS)等更新的和新兴的诊断技术的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/839e/7998255/c17c62dd54bc/diagnostics-11-00479-g001.jpg

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