Lyros Ioannis, Makrygiannakis Miltiadis A, Lykogeorgos Theodoros, Ferdianakis Efstratios, Tsolakis Apostolos I
Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Paediatric Dentist, "Hatzikosta" General Hospital of Messolonghi, 30200 Messolonghi, Greece.
Animals (Basel). 2021 Mar 15;11(3):823. doi: 10.3390/ani11030823.
Treating extreme mandibular growth is challenging. The mandible is pushed backwards to address itsprotrusion. Nevertheless, conclusions after such displacement in animals have been contradictory. The aim of the present review is to present measurable alterations of the mandible and the condyle following retractionin healthy rats or rabbits. PubMed, Scopus and Web of Science were accessed for relevant studies up to October 2020. Eligibility was determined by the PICOS process, while the risk of bias was estimated with SYRCLE's risk of bias tool. Retraction resulted in a more distal molar occlusion and the condyle rested more posteriorly. Mandibular anteroposterior bilateral growth restriction was achieved, the condylar process measured smaller and its angulation increased. The condylar neck thickened, its posterior surface flattened, the coronoid process was measured longer, and enlarged retromolar density was registered. Differences in the ramus height and the intercondylar distance were insignificant. Changes persisted for the period of study and subsequently the mandible resumed its inherited growth pattern. The timing of mandibular shaping and TMJ outcomes might depend on the properties of the applied force. Stability is of concern and well-structured, long-term studies are expected to resolve the issue and further clarify the results of posterior mandibular displacement.
治疗下颌骨过度生长具有挑战性。下颌骨被向后推以解决其前突问题。然而，动物在这种移位后的结论一直相互矛盾。本综述的目的是呈现健康大鼠或兔子下颌骨和髁突在回缩后的可测量变化。检索了截至2020年10月的PubMed、Scopus和Web of Science数据库中的相关研究。通过PICOS流程确定纳入标准，同时使用SYRCLE偏倚风险工具评估偏倚风险。回缩导致磨牙远中咬合更多，髁突向后移位更多。实现了下颌骨前后双侧生长受限，髁突变小且其角度增加。髁突颈部增厚，其后表面变平，冠突变长，磨牙后密度增大。下颌支高度和髁突间距离的差异不显著。这些变化在研究期间持续存在，随后下颌骨恢复其遗传生长模式。下颌骨塑形的时机和颞下颌关节的结果可能取决于所施加力的性质。稳定性令人担忧，预计结构良好的长期研究将解决该问题并进一步阐明下颌骨后移的结果。
