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硬腭黏膜黑色素瘤:手术治疗与重建。

Mucosal Melanoma of the Hard Palate: Surgical Treatment and Reconstruction.

机构信息

Otorhinolaryngology-Head & Neck Surgery Department, San Raffaele Hospital, University Vita-Salute, 20100 Milano, Italy.

School of Medicine, Vita-Salute San Raffaele University, 20100 Milano, Italy.

出版信息

Int J Environ Res Public Health. 2021 Mar 24;18(7):3341. doi: 10.3390/ijerph18073341.

Abstract

Mucosal melanomas of the head and neck region are uncommon pathologies that can affect the oral cavity, and are characterized by a high rate of mortality. Considering the lack of knowledge regarding risk and prognostic factors, current best clinical practice is represented by a large surgical excision with disease-free margins, eventually associated with a reconstructive flap. Indeed, given the frequent necessity of postoperative radiotherapy and fast healing process, a reconstruction of the surgical gap is advisable. Even if several flaps have been most commonly used, the submental island flap represents a valid alternative thanks to local advantages and similar oncologic outcomes compared to free flaps.

摘要

头颈部黏膜黑色素瘤是一种不常见的病理,可影响口腔,其死亡率较高。鉴于对风险和预后因素的了解不足,目前最佳的临床实践是进行大的手术切除,且无肿瘤边缘残留,最终还需进行重建皮瓣。事实上,鉴于术后放疗的必要性以及快速的愈合过程,手术间隙的重建是明智的。尽管有多种皮瓣已被广泛应用,但颏下岛状皮瓣具有局部优势,与游离皮瓣相比具有相似的肿瘤学结果,是一种有效的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac6b/8036556/e690b1f7b78a/ijerph-18-03341-g001.jpg

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