Meraz-Munoz Alejandro, Langote Amit, D Jhaveri Kenar, Izzedine Hassane, Gudsoorkar Prakash
Division of Nephrology, Department of Medicine, St Michael's Hospital, Toronto, ON M5B 1W8, Canada.
Consultant Nephrologist, Apollo Hospital, Navi Mumbai, Maharashtra 400614, India.
Diagnostics (Basel). 2021 Mar 29;11(4):611. doi: 10.3390/diagnostics11040611.
Over the last three decades, advancements in the diagnosis, treatment, and supportive care of patients with cancer have significantly improved their overall survival. However, these advancements have also led to a higher rate of cancer-related complications. Acute kidney injury (AKI) and chronic kidney disease (CKD) are highly prevalent in patients with cancer, and they are associated with an increased risk of all-cause mortality. This bidirectional interplay between cancer and kidney, termed "the kidney-cancer connection" has become a very active area of research. This review aims to provide an overview of some of the most common causes of AKI in patients with cancer. Cancer therapy-associated AKI is beyond the scope of this review and will be discussed separately.
在过去三十年中,癌症患者的诊断、治疗和支持性护理方面的进展显著提高了他们的总体生存率。然而,这些进展也导致了更高的癌症相关并发症发生率。急性肾损伤(AKI)和慢性肾脏病(CKD)在癌症患者中非常普遍,并且它们与全因死亡率增加相关。癌症与肾脏之间的这种双向相互作用,被称为“肾癌关联”,已成为一个非常活跃的研究领域。本综述旨在概述癌症患者急性肾损伤的一些最常见原因。与癌症治疗相关的急性肾损伤不在本综述范围内,将另行讨论。