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内镜下双侧视神经减压术治疗特发性颅内高压

Endoscopic Bilateral Optic Nerve Decompression for Treatment of Idiopathic Intracranial Hypertension.

作者信息

Göksu Ethem, Bozkurt Baran, İlhan Deniz, Özak Ahmet, Çırak Musa, Yağmurlu Kaan

机构信息

Department of Neurosurgery, Akdeniz University, Antalya 07070, Turkey.

Department of Neurosurgery, Acıbadem Mehmet Ali Aydınlar University, Istanbul 34662, Turkey.

出版信息

Brain Sci. 2021 Mar 4;11(3):324. doi: 10.3390/brainsci11030324.

Abstract

OBJECTIVE

To evaluate the results of bilateral endoscopic optic nerve decompression (EOND) with the opening nerve sheath (ONS) technique in patients with idiopathic intracranial hypertension (IIH).

METHODS

Between the years of 2017 and 2019, we retrospectively evaluated nine IIH patients with progressive visual impairment despite medical treatment and who were treated with the EOND and ONS techniques. We also demonstrated our surgical technique recipe on postmortem human heads in a stepwise manner.

RESULTS

There were 9 patients (7 females and 2 males) between the ages of 21 and 72 included in this study, and the mean age was 40.8. All patients had an impairment in visual acuity and/or their visual field, with signs of papilledema and/or optic atrophy. The patients were followed up with for 9-48 months. Improvements in visual acuity were observed in 7 out of 9 patients (78%). Visual field defects improved in 5 out of 8 patients (62.5%). Papilledema was resolved in all patients (100%). Headaches improved in all symptomatic patients (100%). No intraoperative or postoperative complications were observed.

CONCLUSIONS

EOND is a safe and effective surgical procedure in selected patients with IIH. Bilateral wide bony decompression and nerve fenestration can also be an additional benefit for headache relief. Further clinical series and long-term follow-up are needed for more precise results.

摘要

目的

评估采用开放神经鞘(ONS)技术的双侧内镜下视神经减压术(EOND)治疗特发性颅内高压(IIH)患者的效果。

方法

回顾性分析2017年至2019年间9例尽管接受了药物治疗但仍有进行性视力损害且接受了EOND和ONS技术治疗的IIH患者。我们还在尸体头颅上逐步展示了我们的手术技术步骤。

结果

本研究纳入了9例年龄在21至72岁之间的患者(7例女性和2例男性),平均年龄为40.8岁。所有患者均有视力和/或视野损害,伴有视乳头水肿和/或视神经萎缩体征。对患者进行了9至48个月的随访。9例患者中有7例(78%)视力得到改善。8例患者中有5例(62.5%)视野缺损得到改善。所有患者(100%)的视乳头水肿均消退。所有有症状的患者(100%)头痛均改善。未观察到术中或术后并发症。

结论

EOND对选定的IIH患者是一种安全有效的手术方法。双侧广泛的骨性减压和神经开窗术对缓解头痛也可能有额外益处。需要更多的临床系列研究和长期随访以获得更精确的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9231/7998922/3706f15c6395/brainsci-11-00324-g001.jpg

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