Cernasev Alina, Kodidela Sunitha, Veve Michael P, Cory Theodore, Jasmin Hilary, Kumar Santosh
Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Sciences Center, Nashville, TN 37211, USA.
Department of Pharmaceutical Sciences, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Pharmacy (Basel). 2021 Mar 23;9(1):67. doi: 10.3390/pharmacy9010067.
Over the last two decades, the United States (U.S.) has experienced an opioid crisis that has had a significant negative societal and economic impact. Due to the high utilization of opioids in Persons Living with HIV and AIDS (PLWHA), there is a need for a qualitative literature review that presents opioid-use related problems in this population. This study aims to present and identify a thematic overview of the qualitative manuscripts on PLWHA who take opioid medications in the U.S., with a focus on perceptions surrounding medication assisted therapy. The systematic literature search was performed in December 2019. Four databases were searched: PubMed/MEDLINE, Scopus, Web of Science, and Cumulative Index to Nursing & Allied Health Literature (CINAHL). A total of 5348 results were exported from databases into EndNote x9, and duplicates were removed for a total of 3039 unique abstracts to screen. The records were imported into Rayyan, an online platform designed to expedite the screening process. Three authors screened titles and abstracts and determined 19 articles that would be screened in full text. On 9 April 2020, it was determined that eight articles would be included for review. The analysis of the eight manuscripts that fit the inclusion and exclusion criteria revealed barriers and facilitators to medication assisted therapy (MAT) in PLWHA. This review communicates or describes the story of PLWHA who might have delayed access to HIV healthcare providers and the commencement of antiretroviral therapy. In the literature, several studies have focused on the role of physicians in prescribing and addressing the medication regimens but none of the studies examined the role of pharmacists in access to care in this population. Therefore, further research is needed for a better understanding of the social aspects of taking opioid medications in PLWHA and the role of pharmacists within the continuum of care.
在过去二十年中，美国经历了一场阿片类药物危机，这场危机对社会和经济产生了重大负面影响。由于艾滋病毒/艾滋病感染者（PLWHA）对阿片类药物的高使用率，有必要进行一项定性文献综述，以呈现该人群中与阿片类药物使用相关的问题。本研究旨在呈现并确定关于美国服用阿片类药物的艾滋病毒/艾滋病感染者定性手稿的主题概述，重点关注围绕药物辅助治疗的看法。系统文献检索于2019年12月进行。检索了四个数据库：PubMed/MEDLINE、Scopus、科学网和护理及联合健康文献累积索引（CINAHL）。总共从数据库中导出5348条结果到EndNote x9，并删除重复项，共得到3039篇独特摘要进行筛选。这些记录被导入到Rayyan，一个旨在加快筛选过程的在线平台。三位作者筛选了标题和摘要，确定了19篇将进行全文筛选的文章。2020年4月9日，确定将纳入八篇文章进行综述。对符合纳入和排除标准的八篇手稿的分析揭示了艾滋病毒/艾滋病感染者药物辅助治疗（MAT）的障碍和促进因素。本综述传达或描述了艾滋病毒/艾滋病感染者可能延迟获得艾滋病毒医疗服务提供者以及开始抗逆转录病毒治疗的情况。在文献中，有几项研究关注了医生在开处方和处理药物治疗方案方面的作用，但没有一项研究考察药剂师在该人群获得护理方面的作用。因此，需要进一步研究，以更好地理解艾滋病毒/艾滋病感染者服用阿片类药物的社会层面以及药剂师在连续护理中的作用。
