Gretzula J C, Hevia O, Schachner L S, DiLiberti J H, Ruvalcaba R H, Schimschock J R, Weleber R G, Halal F, Lipson M H, Blumberg B
Department of Dermatology, University of Miami School of Medicine, Florida.
Pediatr Dermatol. 1988 Feb;5(1):28-32. doi: 10.1111/j.1525-1470.1988.tb00880.x.
In 1980 a syndrome was first described in two adult males, consisting of macrocephaly, pigmented macules on the glans and shaft of the penis, and hamartomatous intestinal polyps. Since then, 10 additional cases have been identified. Herein, we present two new cases and review the cutaneous manifestations as well as additional features in patients with the Ruvalcaba-Myhre-Smith syndrome.
1980年，一种综合征首次在两名成年男性中被描述，其特征包括巨头畸形、阴茎头和阴茎体上的色素沉着斑以及错构瘤性肠息肉。从那时起，又发现了另外10例病例。在此，我们报告两例新病例，并对鲁瓦尔卡瓦-迈尔-史密斯综合征患者的皮肤表现及其他特征进行综述。
