Martinez J M, Barraquer-Bordas L, Ferrer I, Escartin A E, Rosich M, Barraquer-Feu M L
Service de Neurologie, Hôpital de la Santa Creu i Sant Pau, Barcelone.
Rev Neurol (Paris). 1988;144(2):130-5.
The authors report a patient with Behçet disease who developed severe central neurological disturbances. The M.R.I. was largely coincident with the distribution of the lesions verified in the neuropathological examination, while CT only shows an hypodense lesion in basal ganglia with contrast enhancement. The neurological symptoms did not respond to a treatment with prednisone and azathioprine. The main histopathological findings are similar to those described by previous observers. Reactive histiocytic infiltration with severe lymphocytic phagocytosis, probably related to immunosuppressor treatment, was also observed.
作者报告了一名患有白塞病且出现严重中枢神经功能障碍的患者。磁共振成像（M.R.I.）在很大程度上与神经病理学检查中证实的病变分布一致，而计算机断层扫描（CT）仅显示基底神经节有低密度病变且有强化。神经系统症状对泼尼松和硫唑嘌呤治疗无反应。主要组织病理学发现与先前观察家所描述的相似。还观察到反应性组织细胞浸润伴严重淋巴细胞吞噬现象，这可能与免疫抑制剂治疗有关。
