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[中枢神经系统的HIV感染:精神方面的后果]

[HIV infection of the central nervous system: psychiatric consequences].

作者信息

Schläpfer T E, Fisch H U

机构信息

Psychiatrische Poliklinik der Universität, Bern.

出版信息

Schweiz Med Wochenschr. 1988 Apr 23;118(16):571-6.

PMID:3381071
Abstract

Cerebral infection with human immunodeficiency virus can result in the development of symptoms covering a wide spectrum of psychiatric disorders and including adjustment disorders, affective disorders, delirium and dementia. The rapid and insidious nature of the disease requires an approach that relies on differential diagnosis, thorough psychiatric and neurological examination and, when indicated, additional tests such as EEG, LP, CT or MRI. The treatment of psychiatric symptoms is based on traditional pharmacological principles, although at lower doses due to the patients' propensity to develop delirium. Supportive psychotherapy and education of the patient and his family on the special aspects of HIV-associated psychiatric disorders are also cornerstones of treatment.

摘要

人类免疫缺陷病毒引起的脑部感染可导致一系列精神障碍症状,包括适应障碍、情感障碍、谵妄和痴呆。该疾病快速且隐匿的特性要求采用依赖于鉴别诊断、全面的精神和神经检查的方法,必要时还需进行脑电图(EEG)、腰椎穿刺(LP)、计算机断层扫描(CT)或磁共振成像(MRI)等额外检查。精神症状的治疗基于传统药理学原则,不过鉴于患者易于出现谵妄,用药剂量较低。支持性心理治疗以及对患者及其家属进行关于与HIV相关精神障碍特殊方面的教育也是治疗的基石。

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