Venous Thromboembolism Unit, Internal Medicine. Hospital General Universitario Gregorio Marañón, Madrid, Spain; Department of Medicine, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Venous Thromboembolism Unit, Internal Medicine. Hospital General Universitario Gregorio Marañón, Madrid, Spain; Department of Medicine, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain; Instituto de investigación sanitaria Gregorio Marañón, Madrid, Spain.
Med Clin (Barc). 2021 Jun 25;156(12):622-624. doi: 10.1016/j.medcli.2020.11.039. Epub 2021 Mar 30.
To analyze the prevalence of May-Thurner syndrome (MTS) among patients with deep vein thrombosis (DVT) of left lower limb (LLL), and outcomes after long-term follow-up.
Retrospective observational study that included patients older than 18 diagnosed with acute DVT and MTS.
Among 760 patients diagnosed with DVT in the LLL, 8 patients were diagnosed with MTS (1.05%), with a mean age of 39 years. All patients received long-term anticoagulation, with a mean of 31.9 (±25.2) months. Invasive treatment with pharmaco-mechanical thrombectomy was performed in 5 patients (62.5%). During follow-up (mean of 32.4 months), 25% of patients suffered DVT recurrence. Only 1 case presented major bleeding, and no deaths were registered.
May-Thurner syndrome constitutes a permanent and underdiagnosed risk factor for the development of DVT of LLL. Our findings suggest that long-term anticoagulation therapy might be considered in selected cases.
分析左下肢深静脉血栓形成(DVT)患者中 May-Thurner 综合征(MTS)的患病率,以及长期随访后的结局。
这是一项回顾性观察性研究,纳入了诊断为急性左下肢 DVT 且存在 MTS 的年龄大于 18 岁的患者。
在 760 例诊断为左下肢 DVT 的患者中,有 8 例(1.05%)诊断为 MTS,平均年龄为 39 岁。所有患者均接受了长期抗凝治疗,平均时间为 31.9(±25.2)个月。5 例(62.5%)患者接受了药物机械血栓切除术的有创治疗。在随访期间(平均 32.4 个月),25%的患者出现了 DVT 复发。仅 1 例出现大出血,无死亡病例。
May-Thurner 综合征是左下肢 DVT 发生的永久性、未被充分诊断的危险因素。我们的研究结果提示,在某些特定情况下,可能需要考虑长期抗凝治疗。