异烟肼和乙酰异烟肼在唾液中的稳定性。
Stability of isoniazid and acetylisoniazid in saliva.
作者信息
Hutchings A, Spragg B P, Routledge P A
机构信息
Department of Toxicology, Llandough Hospital, Penarth, S. Glam., U.K.
出版信息
Ther Drug Monit. 1988;10(2):234-6. doi: 10.1097/00007691-198802000-00020.
Abstract
The stability of isoniazid and acetylisoniazid in saliva was studied under various conditions. Acetylisoniazid was stable at 4 degrees, -20 degrees, and -70 degrees C for up to 5 weeks but isoniazid loss was prevented only by storage at -70 degrees C or by addition of azide and storage at 4 degrees C (but not -20 degrees C) for up to 5 weeks.
摘要
在不同条件下研究了异烟肼和乙酰异烟肼在唾液中的稳定性。乙酰异烟肼在4℃、-20℃和-70℃下可稳定保存长达5周，但只有在-70℃下储存或添加叠氮化物并在4℃（而非-20℃）下储存长达5周才能防止异烟肼损失。
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