• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

合成代谢类固醇与极端暴力:慢性摄入并在美替诺龙和群勃龙急性影响下的杀人案。

Anabolic steroids and extreme violence: a case of murder after chronic intake and under acute influence of metandienone and trenbolone.

机构信息

Laboratoire Barla, 6 rue Barla, 06000, Nice, France.

Institut de Médecine Légale, 11 rue Humann, F-67000, Strasbourg, France.

出版信息

Int J Legal Med. 2021 Jul;135(4):1449-1453. doi: 10.1007/s00414-021-02587-y. Epub 2021 Apr 4.

DOI:10.1007/s00414-021-02587-y
PMID:33813613
Abstract

A 32-year-old male went to the police to claim he just killed his girlfriend by inflicting several stabs with a kitchen knife. He was very nervous and particularly aggressive. About 90 min after the assault, a blood specimen was collected with natrium fluoride as preservative. The blood was free of alcohol, pharmaceuticals and drugs of abuse, but tested positive by LC-MS/MS for metandienone (32 ng/mL) and trenbolone (9 ng/mL). The perpetrator admitted regular consumption of anabolic steroids to enhance his muscular mass, as he was a professional security agent. To document long-term steroid abuse, a hair specimen was collected 3 weeks after the assault, which tested positive for both drugs. Segmental analyses revealed in the proximal 1.5 cm segment, corresponding to the period of the assault, the simultaneous presence of metandienone (11 pg/mg) and trenbolone (14 pg/mg), while only metandienone (3 pg/mg) was identified in the distal 1.5 cm segment. As aggressiveness and violence can be associated with abuse of anabolic steroids, the aetiology of this domestic crime was listed to be due impulsive behaviour in a context of antisocial lifestyle.

摘要

一名 32 岁男性到警局报案,称他用厨房刀捅了女友数刀。他非常紧张,而且极具攻击性。袭击发生约 90 分钟后,采集了含有氟化物作为防腐剂的血样。血样中未检出酒精、药物和滥用药物,但通过 LC-MS/MS 检测到甲睾酮(32ng/mL)和群勃龙(9ng/mL)呈阳性。犯罪人承认经常使用合成代谢类固醇来增强肌肉质量,因为他是一名职业保安。为了记录长期使用类固醇的情况,在袭击发生 3 周后采集了头发样本,结果显示两种药物均呈阳性。分段分析显示,在近端 1.5 厘米的部分,同时存在甲睾酮(11pg/mg)和群勃龙(14pg/mg),而在远端 1.5 厘米的部分仅检测到甲睾酮(3pg/mg)。由于攻击性和暴力行为可能与滥用合成代谢类固醇有关,因此将这起家庭犯罪的病因列为在反社会生活方式背景下的冲动行为。

相似文献

1
Anabolic steroids and extreme violence: a case of murder after chronic intake and under acute influence of metandienone and trenbolone.合成代谢类固醇与极端暴力:慢性摄入并在美替诺龙和群勃龙急性影响下的杀人案。
Int J Legal Med. 2021 Jul;135(4):1449-1453. doi: 10.1007/s00414-021-02587-y. Epub 2021 Apr 4.
2
The Power of Keratinous Matrices (Head Hair, Body Hair and Nail Clippings) Analysis in a Case of Death Involving Anabolic Agents.角蛋白基质(头发、体发和指甲屑)分析在涉及合成代谢制剂的死亡案件中的作用。
J Anal Toxicol. 2023 Jan 24;46(9):e307-e313. doi: 10.1093/jat/bkac101.
3
Death after misuse of anabolic substances (clenbuterol, stanozolol and metandienone).滥用合成代谢物质(克仑特罗、司坦唑醇和美雄酮)导致死亡。
Forensic Sci Int. 2019 Oct;303:109925. doi: 10.1016/j.forsciint.2019.109925. Epub 2019 Aug 8.
4
Simultaneous testing for anabolic steroids in human hair specimens collected from various anatomic locations has several advantages when compared with the standard head hair analysis.与标准的头部毛发分析相比,对从不同解剖部位采集的人体毛发样本同时进行合成代谢类固醇检测有几个优点。
Drug Test Anal. 2021 Jul;13(7):1445-1451. doi: 10.1002/dta.3020. Epub 2021 Mar 1.
5
In a Case of Death Involving Steroids, Hair Testing is More Informative than Blood or Urine Testing.在涉及类固醇的死亡案例中,毛发检测比血液或尿液检测提供更多信息。
J Anal Toxicol. 2021 Sep 17;45(8):829-834. doi: 10.1093/jat/bkab048.
6
Doping control for metandienone using hair analyzed by gas chromatography-tandem mass spectrometry.使用气相色谱-串联质谱法分析毛发来检测美雄酮的兴奋剂控制。
J Chromatogr B Analyt Technol Biomed Life Sci. 2006 May 19;836(1-2):124-8. doi: 10.1016/j.jchromb.2006.03.040. Epub 2006 Apr 4.
7
'My mind pretty much went to mush': A qualitative exploration of trenbolone in the performance and image enhancing drug community.“我的脑子几乎一片混乱”:在性能和形象增强药物社区中使用 trenbolone 的定性探索。
Drug Alcohol Rev. 2023 Sep;42(6):1566-1576. doi: 10.1111/dar.13656. Epub 2023 Mar 29.
8
Detection and quantification of 12 anabolic steroids and analogs in human whole blood and 20 in hair using LC-HRMS/MS: application to real cases.使用液相色谱-高分辨质谱/质谱法检测和定量人全血中的12种合成代谢类固醇及其类似物以及毛发中的20种:在实际案例中的应用
Int J Legal Med. 2017 Jul;131(4):989-999. doi: 10.1007/s00414-017-1552-3. Epub 2017 Feb 24.
9
The dark side of beauty: acne fulminans induced by anabolic steroids in a male bodybuilder.美的阴暗面:一名男性健美运动员使用合成代谢类固醇引发暴发性痤疮。
Arch Dermatol. 2012 Oct;148(10):1210-2. doi: 10.1001/archdermatol.2012.855.
10
Testing for anabolic steroids in human nail clippings.人体指甲剪片中合成代谢类固醇的检测。
J Forensic Sci. 2021 Jul;66(4):1577-1582. doi: 10.1111/1556-4029.14729. Epub 2021 Apr 22.

本文引用的文献

1
Hair testing for acetazolamide as an evidence of the use of a contaminated dietary supplement.检测头发中的乙酰唑胺以证明使用了受污染的膳食补充剂。
Drug Test Anal. 2021 Aug;13(8):1584-1588. doi: 10.1002/dta.3100. Epub 2021 May 28.
2
Anabolic steroids-induced delirium: A case report.合成代谢类固醇所致谵妄:一例报告。
Medicine (Baltimore). 2020 Aug 14;99(33):e21639. doi: 10.1097/MD.0000000000021639.
3
Death after misuse of anabolic substances (clenbuterol, stanozolol and metandienone).滥用合成代谢物质(克仑特罗、司坦唑醇和美雄酮)导致死亡。
Forensic Sci Int. 2019 Oct;303:109925. doi: 10.1016/j.forsciint.2019.109925. Epub 2019 Aug 8.
4
Hair Analysis in Forensic Toxicology: An Updated Review with a Special Focus on Pitfalls.法医毒理学中的毛发分析:更新综述及特别关注的陷阱。
Curr Pharm Des. 2017;23(36):5480-5486. doi: 10.2174/1381612823666170929155628.
5
Aggression: the testosterone-serotonin link.攻击性:睾酮与血清素的联系。
Isr Med Assoc J. 2003 Sep;5(9):653-8.