Agarwal Rachna, Goyal Penzy, Mohta Medha, Kar Rajarshi
Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, 110095 India.
Department of Anaesthesia, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, 110095 India.
J Obstet Gynaecol India. 2021 Feb;71(1):45-51. doi: 10.1007/s13224-020-01375-9. Epub 2020 Sep 25.
We aimed to determine performance of sequential organ failure assessment (SOFA) and Sepsis in Obstetrics Score (SOS), in women with pregnancy-associated sepsis (PAS) with respect to critical care admission and mortality.
Obstetric patients with PAS fulfilling any 2 of the quick SOFA (qSOFA) criteria were enrolled as cases. The various parameters of SOFA and SOS were recorded at admission and compared for outcomes.
Critical care was required in 32 (50.7%) patients and associated mortality was high (31.7%). For our study population, a threshold of SOFA ≥ 6 had the best combination of sensitivity (84.4%) and specificity (61.3%) for critical care admission. For SOS, a cut-off value of ≥ 6 gave best sensitivity (64%) and specificity (40%) for the same.
SOFA was far more predictive of patient's critical condition as well as mortality compared to SOS. SOFA was superior to SOS in determining critical care admission and mortality for PAS.
我们旨在确定序贯器官衰竭评估（SOFA）和产科脓毒症评分（SOS）在妊娠相关脓毒症（PAS）女性患者中对于重症监护病房收治情况和死亡率的预测性能。
符合快速SOFA（qSOFA）标准中任意两条的PAS产科患者被纳入病例组。记录入院时SOFA和SOS的各项参数，并比较其预后情况。
32例（50.7%）患者需要重症监护，且相关死亡率较高（31.7%）。对于我们的研究人群，SOFA≥6的阈值对于重症监护病房收治情况具有最佳的敏感性（84.4%）和特异性（61.3%）组合。对于SOS，截断值≥6对于重症监护病房收治情况具有最佳的敏感性（64%）和特异性（40%）。
与SOS相比，SOFA对于患者的危急状况和死亡率的预测性要强得多。在确定PAS患者的重症监护病房收治情况和死亡率方面，SOFA优于SOS。
