Khan Majid, Farnsworth Brian, Pope Brandon R, Sherrod Brandon, Karsy Michael
Department of Medicine, Reno School of Medicine, University of Nevada, Reno, USA.
Department of Neurosurgery, University of Utah, Salt Lake City, USA.
Cureus. 2021 Feb 28;13(2):e13617. doi: 10.7759/cureus.13617.
Introduction Hydrocephalus remains a common condition with significant patient morbidity; however, accurate accounting of the incidence of this disease as well as of the impact of hospital volume on outcome remains limited. Methods The National Inpatient Sample was used to evaluate patients who underwent surgical treatment of hydrocephalus from 2009-2013. Patient demographics (e.g., length of stay, disposition, charges), and the impact of hospital volume on outcomes were evaluated. Results A total of 156,205 patients were identified. Ventriculoperitoneal (VP) shunting the most common type of device (35.8%) followed by shunt replacement (23.9%). Treatment charges for hydrocephalus were $332 million in 2009 and $418 million in 2013 nationally. High-volume hospitals had more routine discharges compared with lower-volume hospitals (65.7% vs. 50.9%, p<0.0001), which was a trend that improved over time. Multivariate analysis confirmed that hospital volume was independently associated with routine disposition after adjusting for other factors such as patient age, length of stay, and shunt type. However, hospital volume showed a small association with length of stay (β = -0.05, p = 0.0001) and did not impact hospital charges on multivariate analysis. Conclusion This analysis provides a recent update of hydrocephalus epidemiology, trends, and outcomes nationally. Estimates from this study suggest that hydrocephalus is a common and costly problem. Hospital volume was for the first time to be associated with important differences in patient outcomes.
引言 脑积水仍然是一种常见疾病,会给患者带来严重的发病率;然而,对这种疾病的发病率以及医院规模对治疗结果的影响进行准确统计仍然有限。方法 利用国家住院患者样本评估2009年至2013年接受脑积水手术治疗的患者。评估了患者人口统计学特征(如住院时间、出院情况、费用)以及医院规模对治疗结果的影响。结果 共识别出156,205例患者。脑室腹腔(VP)分流是最常见的治疗方式(35.8%),其次是分流器置换(23.9%)。2009年全国脑积水治疗费用为3.32亿美元,2013年为4.18亿美元。与低规模医院相比,高规模医院的常规出院患者更多(65.7%对50.9%,p<0.0001),且这一趋势随时间有所改善。多变量分析证实,在调整患者年龄、住院时间和分流类型等其他因素后,医院规模与常规出院情况独立相关。然而,医院规模与住院时间的关联较小(β = -0.05,p = 0.0001),在多变量分析中对医院费用没有影响。结论 本分析提供了全国范围内脑积水流行病学、趋势和治疗结果的最新情况。本研究的估计表明,脑积水是一个常见且成本高昂的问题。医院规模首次与患者治疗结果的重要差异相关联。