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免疫功能低下患者的双重打击。

A double whammy in an immunocompromised patient.

作者信息

Baburao Archana, Singh Amandeep, Narayanswamy Huliraj, Shivalingaiah Bhavya

机构信息

Department of Pulmonary Medicine, Kempegowda Institute of Medical Sciences, Bengaluru, Karnataka, India.

出版信息

Indian J Sex Transm Dis AIDS. 2020 Jul-Dec;41(2):201-204. doi: 10.4103/ijstd.IJSTD_70_18. Epub 2020 Nov 11.

Abstract

Pneumocystis jirovecii pneumonia (PCP) is a common opportunistic infection in immunocompromised patients, especially those with human immunodeficiency virus (HIV) infection. (CMV) pneumonia most often occurs as a coinfection with another opportunistic pathogen especially in patients with severe immunosuppression. We present a case of PCP-CMV coinfection in a newly diagnosed HIV patient who was treated with the recommended therapy for both diseases and had a favorable outcome. The presence of CMV in the context of another opportunistic respiratory tract infection is often to be not treated, due to conflicting evidence of its therapeutic benefit. Our report highlights the importance of CMV treatment to achieve clinical stability and recovery in newly diagnosed patients with HIV and severely immuno-compromised status.

摘要

耶氏肺孢子菌肺炎(PCP)是免疫功能低下患者常见的机会性感染,尤其是人类免疫缺陷病毒(HIV)感染者。巨细胞病毒(CMV)肺炎最常作为与另一种机会性病原体的合并感染出现,特别是在严重免疫抑制的患者中。我们报告了一例新诊断的HIV患者发生PCP-CMV合并感染的病例,该患者接受了针对两种疾病的推荐治疗,预后良好。在另一种机会性呼吸道感染的情况下,由于CMV治疗益处的证据相互矛盾,其感染通常不进行治疗。我们的报告强调了CMV治疗对于新诊断的HIV且严重免疫功能低下患者实现临床稳定和康复的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b63e/8000680/8ba503903d6c/IJSTD-41-201-g001.jpg

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