From the National Clinical Research Center for Mental Disorders, and Department of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.
Psychosom Med. 2021 May 1;83(4):387-396. doi: 10.1097/PSY.0000000000000922.
This study aimed to quantify the prevalence of the adverse mental health outcomes in medical staff working in the hospital settings during the coronavirus disease 2019 (COVID-19) pandemic and explore the relative distribution of anxiety and depressive symptoms.
PubMed, EMBASE, China National Knowledge Infrastructure, WANFANG DATA, and VIP Database for Chinese Technical Periodicals were searched for articles published from January 1, 2019, to April 19, 2020. The prevalence estimates of adverse mental health symptoms in medical staff were pooled using the random-effects model.
A total of 35 articles and data of 25,343 medical staff were used in the final analysis. The pooled prevalence estimates in medical staff during the COVID-19 pandemic were as follows (ordered from high to low): fear-related symptoms, 67% (95% confidence interval [CI] = 61%-73%); high levels of perceived stress, 56% (95% CI = 32%-79%), anxiety symptoms, 41% (95% CI = 35%-47%); insomnia, 41% (95% CI = 33%-50%); posttraumatic stress disorder symptoms, 38% (95% CI = 34%-43%); depressive symptoms, 27% (95% CI = 20%-34%); and somatic symptoms, 16% (95% CI = 3%-36%). The subgroup analysis revealed that the prevalence estimates of fear-related symptoms were consistently high.
Medical staff during the COVID-19 epidemic have a high prevalence of adverse mental health symptoms. Data-based strategies are needed to optimize mental health of medical staff and other health care professionals during times of high demand such as the COVID-19 and other epidemics.PROSPERO Registration: CRD42020182433.
本研究旨在量化 2019 年冠状病毒病（COVID-19）大流行期间医院工作人员不良心理健康结局的流行情况，并探讨焦虑和抑郁症状的相对分布。
检索 2019 年 1 月 1 日至 2020 年 4 月 19 日发表的文献，检索数据库包括 PubMed、EMBASE、中国知识基础设施、万方数据和维普中文科技期刊数据库。使用随机效应模型汇总医务人员不良心理健康症状的患病率估计值。
共纳入 35 篇文章和 25343 名医务人员的数据进行最终分析。COVID-19 大流行期间医务人员的汇总患病率估计值如下（从高到低排序）：恐惧相关症状，67%（95%置信区间[CI] = 61%-73%）；高水平的感知压力，56%（95% CI = 32%-79%），焦虑症状，41%（95% CI = 35%-47%）；失眠，41%（95% CI = 33%-50%）；创伤后应激障碍症状，38%（95% CI = 34%-43%）；抑郁症状，27%（95% CI = 20%-34%）；躯体症状，16%（95% CI = 3%-36%）。亚组分析显示，恐惧相关症状的患病率估计值一直较高。
COVID-19 流行期间，医务人员不良心理健康症状的患病率较高。需要基于数据的策略来优化医务人员和其他卫生保健专业人员在高需求时期（如 COVID-19 和其他流行病）的心理健康。
PROSPERO 注册：CRD42020182433。
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