School of Medicine, University of Concepción, Concepción, Chile.
Endocrinology Section, Department of Internal Medicine, School of Medicine, University of Concepción, Concepción, Chile.
Osteoporos Int. 2021 Oct;32(10):2033-2041. doi: 10.1007/s00198-021-05910-w. Epub 2021 Apr 5.
Data linking solar radiation with fractures are lacking. We found that lower solar radiation was associated with higher hip fracture admission rates in men from Chile. This supports the idea that solar radiation, a surrogate of vitamin D, may be involved in the development of fractures in older population. INTRODUCTION : To explore the associations between solar radiation and latitude with hip fracture admission rates in people aged 65 years or older in Chile, the country with the greatest variation in solar radiation in the world.
In this ecological study, we investigated the associations between regional solar radiation and latitude with hospitalizations due to hip fracture in population aged 65 years or older, by reviewing national records between 2013 and 2018. We also evaluated the role of sociodemographic factors such as poverty, education, indigenous ethnicity, and rurality rates.
Between 2013 and 2018, there were 44,328 admissions due to hip fracture in people aged 65 years or older; 77.5% were women and 65.1% were aged 80 years or older. The national admission rate was 389.3 per 100,000 inhabitants (95% CI: 382.4-396.2). The highest admission rate was registered in the Region IX (445.3 per 100,000, 95% CI: 398.3-492.4), which has the highest poverty rates, indigenous ethnicity rates, and rurality rates. We found a north-south increasing gradient of admission rates in men (β=1.5 [95% CI: 0 to 3], p=0.044) and a significant association between solar radiation and admission rates in men (β=-4.4 [95% CI: -8 to 0.8], p=0.02). Admission rates in men were also associated with sociodemographic variables such as poverty (β=2.4 [95% CI: 0 to 4.8], p=0.048) and rurality rates (β=1.2 [95% CI: 0.1 to 2.4], p=0.039).
Regional solar radiation and latitude were associated with hip fracture admission rates in men aged 65 years or older in Chile, with highest admission rates at higher latitudes and lower solar radiation.
探索智利 65 岁及以上人群中，太阳辐射与纬度与髋部骨折入院率之间的关系，智利是世界上太阳辐射变化最大的国家。
在这项生态学研究中，我们通过查阅 2013 年至 2018 年的国家记录，研究了区域太阳辐射与纬度与 65 岁及以上人群髋部骨折住院率之间的关系。我们还评估了贫困、教育、土著民族和农村化率等社会人口因素的作用。
2013 年至 2018 年期间，65 岁及以上人群中有 44328 人因髋部骨折入院；77.5%为女性，65.1%为 80 岁及以上。全国入院率为 389.3/10 万居民（95%CI：382.4-396.2）。入院率最高的是第九区（445.3/10 万，95%CI：398.3-492.4），该地区贫困率、土著民族率和农村化率最高。我们发现男性的入院率呈北-南递增梯度（β=1.5[95%CI：0-3]，p=0.044），并且男性的太阳辐射与入院率之间存在显著相关性（β=-4.4[95%CI：-8-0.8]，p=0.02）。男性的入院率还与社会人口学变量如贫困（β=2.4[95%CI：0-4.8]，p=0.048）和农村化率（β=1.2[95%CI：0.1-2.4]，p=0.039）相关。
在智利，65 岁及以上男性的区域太阳辐射和纬度与髋部骨折入院率相关，纬度较高和太阳辐射较低的地区入院率较高。
