Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur, India.
FEBS J. 2021 Apr;288(8):2458-2460. doi: 10.1111/febs.15839. Epub 2021 Apr 5.
This Special Issue of The FEBS Journal brings together a set of review articles focused on recent developments in the field of GPCR biology, with particular emphasis on novel paradigms of their activation, signaling, and regulation. These articles cover a broad repertoire of cellular, physiological, and structural aspects ranging from the interaction of GPCRs with their signal transducers, allosteric modulation of these receptors with therapeutic implications, and emerging technologies aimed to probe critical aspects of receptor signaling and regulation.
本期 FEBS 杂志特刊汇集了一系列评论文章，重点关注 GPCR 生物学领域的最新发展，特别强调它们激活、信号转导和调节的新范例。这些文章涵盖了从 GPCR 与其信号转导器的相互作用、这些受体的变构调节及其具有治疗意义，到旨在探索受体信号转导和调节关键方面的新兴技术等广泛的细胞、生理和结构方面。
