Department of Internal Medicine, Atlantic Health System, Morristown, NJ, USA.
Department of Cardiology, Atlantic Health System, Morristown, NJ, USA.
Am J Med Sci. 2021 Aug;362(2):215-219. doi: 10.1016/j.amjms.2021.03.014. Epub 2021 Apr 2.
Takotsubo cardiomyopathy (TCM), or stress induced cardiomyopathy is being increasingly recognized as a cause of acute heart failure. Often seen in women and older individuals with acute stressors, it can cause significant hemodynamic compromise. Here we report a case of a 78 year old woman who developed sudden chest pain following radiation therapy for B-Cell lymphoma. Echocardiogram revealed newly reduced ejection fraction and cardiac catheterization showed non obstructive coronary disease. Left ventriculogram revealed apical ballooning, characteristic of TCM. Often linked to physical and emotional stressors, TCM has been found to be more prevalent in patients with malignancies.
心尖球囊样综合征（TCM）又称应激性心肌病，正越来越多地被认为是急性心力衰竭的一个病因。该病常发生于女性和有急性应激源的老年患者，可导致显著的血流动力学障碍。在此我们报告一例 78 岁女性，在因 B 细胞淋巴瘤接受放射治疗后突发胸痛。超声心动图显示射血分数突然降低，而心导管检查显示无阻塞性冠状动脉疾病。左心室造影显示心尖球囊样改变，符合 TCM 的特征。TCM 通常与身体和情绪应激源相关，已发现其在恶性肿瘤患者中更为普遍。
