Hagemann H D, Prass D, Hausdörfer J
Abteilung Anaesthesie III, Medizinische Hochschule Hannover.
Anaesthesist. 1988 Mar;37(3):193-5.
The central cholinergic syndrome developed in a 5 1/2-year-old child after premedication with midazolam and a short volatile anesthetic. Diagnosis was made more difficult because of a history of nephrotic syndrome, convulsions, relative acetylcholinesterase deficiency and chronic medication with a corticosteroid. Successful management of such cases depends on a through differential diagnosis before the institution of physostigmine therapy. Intensive postoperative monitoring is strongly recommended.
一名5岁半的儿童在使用咪达唑仑进行术前用药和吸入短效挥发性麻醉剂后出现了中枢性胆碱能综合征。由于该患儿有肾病综合征、惊厥、相对乙酰胆碱酯酶缺乏病史以及长期使用皮质类固醇药物,使得诊断更加困难。此类病例的成功处理取决于在使用毒扁豆碱治疗之前进行全面的鉴别诊断。强烈建议术后进行密切监测。