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轴向型脊柱关节炎的关节解剖:骶髂关节形态变化与症状性疾病之间存在强关联。

Joint anatomy in axial spondyloarthritis: strong associations between sacroiliac joint form variation and symptomatic disease.

机构信息

Department of Radiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Department of Radiology, Vivantes Klinikum am Friedrichshain, Berlin, Germany.

出版信息

Rheumatology (Oxford). 2021 Dec 24;61(1):388-393. doi: 10.1093/rheumatology/keab318.

DOI:10.1093/rheumatology/keab318
PMID:33822902
Abstract

OBJECTIVES

The aim of this investigation was to determine the prevalence of variant SI joint forms in symptomatic patients with mechanical joint disease (MJD) and axial SpA (axSpA) compared with control patients.

METHOD

A total of 973 patients were included in this cross-sectional study (95 axSpA; 61 MJD; 817 controls); clinical diagnosis, age and gender were noted. An established scoring system was used to classify joint forms on CT scans of the pelvis. Frequencies of joint forms were compared between groups (axSpA; MJD; controls).

RESULTS

Patients with MJD exhibited the highest proportion of atypical joints (80.3% in MJD vs 44.1% in axSpA and 37.5% in controls; P < 0.001). Overall, females had a significantly higher proportion of atypical joints than men (65.0 vs 17.8%; P < 0.001); proportions of atypical joints were significantly higher in males with symptomatic joint disease than in male controls: 32.2% in axSpA, 55.0% in MJD and 13.9% in controls; P ≤ 0.001. Two specific joint forms were significantly more prevalent in symptomatic patients than in controls: the iliosacral complex (16.2 vs 4.2%; P < 0.001) and the crescent-shaped ilium (9.1 vs 2.8%; P < 0.05).

CONCLUSIONS

Our data demonstrate a strong association between atypical joint forms and symptomatic joint disease.

摘要

目的

本研究旨在比较机械性关节疾病(MJD)和中轴型脊柱关节炎(axSpA)的症状性患者与对照组患者之间变体骶髂关节(SI)形式的流行率。

方法

本横断面研究共纳入 973 例患者(95 例 axSpA;61 例 MJD;817 例对照组);记录了临床诊断、年龄和性别。使用既定的评分系统对骨盆 CT 扫描中的关节形式进行分类。比较各组(axSpA;MJD;对照组)的关节形式频率。

结果

MJD 患者表现出最高比例的非典型关节(80.3%在 MJD 中,44.1%在 axSpA 中,37.5%在对照组中;P<0.001)。总体而言,女性的非典型关节比例明显高于男性(65.0%比 17.8%;P<0.001);有症状性关节疾病的男性中,非典型关节的比例明显高于男性对照组:axSpA 中为 32.2%,MJD 中为 55.0%,对照组中为 13.9%;P≤0.001。两种特定的关节形式在症状性患者中比在对照组中更为普遍:骶髂复合体(16.2%比 4.2%;P<0.001)和新月形髂骨(9.1%比 2.8%;P<0.05)。

结论

我们的数据表明,非典型关节形式与症状性关节疾病之间存在很强的关联。

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