Akiyama K, Sawatani O, Imamura E, Endo M, Hashimoto A, Koyanagi H
Department of Cardiovascular Surgery, Tokyo Women's Medical College, Japan.
Ann Thorac Surg. 1988 Jul;46(1):73-8. doi: 10.1016/s0003-4975(10)65857-2.
Stent creep, often associated with valve malfunction, is said to play an important role in the long-term performance of a porcine bioprosthesis. We have measured the angle of the stent post showing maximal inward bending (IBA) on 44 mitral porcine bioprostheses. All of them were explanted 1 to 12 years (mean explant time, 7.8 years) postoperatively at reoperation. Patients included 19 men and 25 women, ranging in age from 24 to 66 years (mean age, 47.2 years). Mean IBA was 12.7 +/- 4.2 [SD] degrees in 14 valves implanted for 7 years or less and 16.4 +/- 5.8 degrees in 30 valves implanted 8 years or longer (p less than 0.05). There was no significant difference in IBA among valves based on type (25 Hancock valves, 15.0 +/- 4.7 degrees; 10 Angell-Shiley valves, 16.2 +/- 8.6 degrees; and 9 Carpentier-Edwards valves, 14.4 +/- 3.7 degrees). There was a significant difference in IBA based on valve size (37 valves measuring 25-29 mm in diameter, 16.3 +/- 5.1 degrees; and 7 valves measuring 31 mm in diameter, 9.9 +/- 5.1 degrees; p less than 0.05). IBA showed a tendency to have a large value in a heart with a small left ventricular end-systolic volume. We conclude that (1) stent creep is not related to the materials or designs of the stent post, but tends to increase with passage of time in place; and (2) compression of the left ventricular wall is one of the main causes of stent-post bending.
支架蠕变常与瓣膜功能障碍相关,据说在猪生物瓣膜的长期性能中起重要作用。我们测量了44个猪二尖瓣生物瓣膜上显示最大向内弯曲(IBA)的支架柱角度。所有瓣膜均在术后1至12年(平均取出时间为7.8年)再次手术时取出。患者包括19名男性和25名女性,年龄在24至66岁之间(平均年龄47.2岁)。植入7年或更短时间的14个瓣膜的平均IBA为12.7±4.2[标准差]度,植入8年或更长时间的30个瓣膜的平均IBA为16.4±5.8度(p<0.05)。基于瓣膜类型,各瓣膜间的IBA无显著差异(25个Hancock瓣膜,15.0±4.7度;10个Angell-Shiley瓣膜,16.2±8.6度;9个Carpentier-Edwards瓣膜,14.4±3.7度)。基于瓣膜大小,IBA有显著差异(37个直径为25-29mm的瓣膜,16.3±5.1度;7个直径为31mm的瓣膜,9.9±5.1度;p<0.05)。在左心室收缩末期容积较小的心脏中,IBA往往有较大值。我们得出结论:(1)支架蠕变与支架柱的材料或设计无关,但往往会随着植入时间的推移而增加;(2)左心室壁的压迫是支架柱弯曲的主要原因之一。