Schön Christiane, Reule Claudia, Knaub Katharina, Micka Antje, Wilhelm Manfred, Alt Wilfried, Menzel Daniel
BioTeSys GmbH, Schelztorstraße 54-56, 73728, Esslingen, Baden-Württemberg, Germany.
Department of Mathematics, Natural and Economic Sciences, Ulm University of Applied Sciences, Albert-Einstein-Allee 55, 89081, Ulm, Baden-Württemberg, Germany.
Sports Med Open. 2021 Apr 6;7(1):24. doi: 10.1186/s40798-021-00317-7.
The assessment of improvement or maintenance of joint health in healthy subjects is a great challenge. The aim of the study was the evaluation of a joint stress test to assess joint discomfort in subjects with activity-related knee joint discomfort (ArJD).
Forty-five subjects were recruited to perform the single-leg-step-down (SLSD) test (15 subjects per group). Subjects with ArJD of the knee (age 22-62 years) were compared to healthy subjects (age 24-59 years) with no knee joint discomfort during daily life sporting activity and to subjects with mild-to-moderate osteoarthritis of the knee joint (OA, Kellgren score 2-3, age 42-64 years). The subjects performed the SLSD test with two different protocols: (I) standardization for knee joint discomfort; (II) standardization for load on the knee joint. In addition, range of motion (ROM), reach test, acute pain at rest and after a single-leg squat and knee injury, and osteoarthritis outcome score (KOOS) were assessed. In OA and ArJD subjects, knee joint discomfort could be reproducibly induced in a short time interval of less than 10 min (200 steps). In healthy subjects, no pain was recorded. A clear differentiation between study groups was observed with the SLSD test (maximal step number) as well as KOOS questionnaire, ROM, and reach test. In addition, a moderate to good intra-class correlation was shown for the investigated outcomes.
These results suggest the SLSD test is a reliable tool for the assessment of knee joint health function in ArJD and OA subjects to study the improvements in their activities. Further, this model can be used as a stress model in intervention studies to study the impact of stress on knee joint health function.
评估健康受试者关节健康的改善或维持情况是一项巨大挑战。本研究的目的是评估一种关节压力测试，以评估有活动相关膝关节不适（ArJD）的受试者的关节不适情况。
招募了45名受试者进行单腿下蹲（SLSD）测试（每组15名受试者）。将患有膝关节ArJD的受试者（年龄22 - 62岁）与在日常生活体育活动中无膝关节不适的健康受试者（年龄24 - 59岁）以及患有轻度至中度膝关节骨关节炎（OA，Kellgren评分2 - 3，年龄42 - 64岁）的受试者进行比较。受试者按照两种不同方案进行SLSD测试：（I）针对膝关节不适进行标准化；（II）针对膝关节负荷进行标准化。此外，还评估了关节活动范围（ROM）、伸展测试、静息及单腿蹲后急性疼痛和膝关节损伤情况，以及骨关节炎结局评分（KOOS）。在OA和ArJD受试者中，可在不到10分钟（200步）的短时间间隔内重现膝关节不适。在健康受试者中，未记录到疼痛。通过SLSD测试（最大步数）以及KOOS问卷、ROM和伸展测试观察到各研究组之间有明显差异。此外，所研究的结局显示出中度至良好的组内相关性。
这些结果表明，SLSD测试是评估ArJD和OA受试者膝关节健康功能以研究其活动改善情况的可靠工具。此外，该模型可作为干预研究中的压力模型，以研究压力对膝关节健康功能的影响。
