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扩大经鼻内镜鞍内及鞍旁入路治疗侵袭性垂体瘤的技术及挑战。

Techniques and challenges of the expanded endoscopic endonasal sellar and parasellar approaches to invasive pituitary tumors.

机构信息

Department of Neurological Surgery, The Ohio State University Medical Center, N-1049 Doan Hall, 410 West 10th Avenue, Columbus, OH, 43210, USA.

Department of Pediatric Endocrinology, Nationwide Children's Hospital, Columbus, OH, USA.

出版信息

Acta Neurochir (Wien). 2021 Jun;163(6):1717-1723. doi: 10.1007/s00701-021-04805-3. Epub 2021 Apr 7.

Abstract

BACKGROUND

Superb knowledge of surgical anatomy and nuances to remove the natural barriers preventing full access to the paramedian skull base determines the ease of using the expanded sellar/parasellar approaches as the main gateway for all the parasagittal modules during endoscopic endonasal access (EEA) to pituitary tumors with cavernous sinus (CS) invasion.

METHODS

Throughout stepwise-cadaveric dissections and pertinent intraoperative analysis, we describe surgical pearls and pitfalls of the parasellar-EEA with special references to the utility of various lines/classifications on neuroimaging correlated with strategies to enhance surgical safety and tumor resection.

CONCLUSION

EEA to invasive parasellar pathologies needs to address strict bleeding control and displacement of neurovascular structures inside the CS, posing a chance for neurologic morbidities/ICA injury. Meticulous utilization of operative landmarks and strategies can help avoid and mitigate surgical complications.

摘要

背景

精湛的手术解剖知识和细微之处,可以消除阻碍充分进入旁正中颅底的天然屏障,这决定了在经鼻内镜颅底手术(EEA)中,扩大的鞍旁/鞍旁区域入路作为所有矢状窦旁模块的主要入路的难易程度,对于伴有海绵窦(CS)侵犯的垂体瘤而言更是如此。

方法

通过逐步的尸体解剖和相关的术中分析,我们描述了鞍旁-EEA 的手术要点和陷阱,特别提到了神经影像学上各种线/分类的应用,以及增强手术安全性和肿瘤切除的策略。

结论

对于侵袭性鞍旁病变的 EEA 需要解决严格的出血控制和 CS 内神经血管结构的移位问题,这有可能导致神经功能障碍/ICA 损伤。精细地利用手术标志和策略可以帮助避免和减轻手术并发症。

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