From the Department of Nuclear Medicine, Affiliated Hospital of Southwest Medical University; Nuclear Medicine and Molecular Imaging Key Laboratory of Sichuan Province; and Academician (Expert) Workstation of Sichuan Province, Luzhou, Sichuan, People's Republic of China.
Clin Nucl Med. 2021 Jun 1;46(6):523-524. doi: 10.1097/RLU.0000000000003632.
68Ga-labeled quinoline-based fibroblast activation protein inhibitors (68Ga-FAPIs) has been used in the evaluation of a variety of malignancies. We report the case of a patient with rib plasmacytoma, which showed elevated 68Ga-FAPI activity. This case indicated fibroblast activation protein overexpression and some degree of fibrosis in the plasmacytoma lesion. Therefore, 68Ga-FAPI can be a potential tracer in the evaluation of plasmacytoma.
68Ga 标记的喹啉类成纤维细胞激活蛋白抑制剂（68Ga-FAPIs）已被用于多种恶性肿瘤的评估。我们报告了一例肋骨浆细胞瘤患者，其 68Ga-FAPI 活性升高。该病例表明浆细胞瘤病变中存在成纤维细胞激活蛋白过表达和一定程度的纤维化。因此，68Ga-FAPI 可能成为评估浆细胞瘤的一种潜在示踪剂。
