Group B streptococcal meningitis: delayed response to treatment.

Four infants with group B streptococcal meningitis had a delayed response to antibiotic therapy. Resolution of cerebrospinal fluid infection and/or pleocytosis occurred only after prolonged and intensive antimicrobial management. In this respect, these infants were similar to infants with gram-negative enteric meningitis. It is suggested that infants with group B streptococcal meningitis be closely monitored to insure adequate response to therapy.