Hartveit F, Skarstein A, Varhaug J E
Department of Pathology, Gade Institute, Bergen, Norway.
Breast Cancer Res Treat. 1988 Apr;11(1):71-5. doi: 10.1007/BF01807561.
The findings on routine pre-operative palpation of the axilla in patients with infiltrative breast carcinoma are compared to the results of histological quantitation of the nodal lymphoid tissue and its tumour deposits in 91 consecutive cases in which a standardized axillary dissection had been carried out. The study demonstrates that lymphoid tissue, even when present in large amounts (up to 6 cm2 on histology), is seldom palpable. What the clinician identifies in favourable cases is the tumour deposit itself. When little lymphoid tissue is present very small tumour deposits (0.2 cm2) may be found on palpation, but large deposits (1 cm2) may be missed when surrounded by sufficient lymphoid tissue. These findings go far to explain the well documented unreliability of the nodal findings on axillary palpation in breast cancer.
将浸润性乳腺癌患者术前常规腋窝触诊结果与91例连续进行标准化腋窝清扫病例的淋巴结淋巴组织及其肿瘤沉积物的组织学定量结果进行比较。该研究表明，即使淋巴组织大量存在（组织学上可达6平方厘米），也很少能触诊到。在有利的病例中，临床医生所触诊到的是肿瘤沉积物本身。当淋巴组织很少时，触诊可能会发现非常小的肿瘤沉积物（0.2平方厘米），但当被足够的淋巴组织包围时，大的沉积物（1平方厘米）可能会被漏诊。这些发现充分解释了乳腺癌腋窝触诊淋巴结结果不可靠这一有充分记录的情况。
