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肥胖和超重孕妇在妊娠和产褥期的母婴结局。一项队列研究。

Maternal and fetal outcomes during pregnancy and puerperium in obese and overweight pregnant women. A cohort study.

机构信息

Department of Obstetrics and Gynecology, Hospital Universitario Lucus Augusti. C/Ulises, Romero nº1, 27003, Lugo, Spain.

出版信息

Arch Gynecol Obstet. 2021 Nov;304(5):1205-1212. doi: 10.1007/s00404-021-06059-x. Epub 2021 Apr 8.

Abstract

PURPOSE

compare incidences of maternal-fetal complications during pregnancy, labor, and early puerperium according to baseline BMI in a consecutive cohort of pregnant women.

METHODS

This retrospective cohort study compares pregnancy outcome indicators by body mass index (BMI) in 1236 pregnant women managed over the period January 2017 to May 2018. Data were collected regarding the personal history (smoking, diabetes and hypertension), obstetrics and BMI (kg/m) (normoweight 18.5-24.9, overweight 25-29.9, obese ≥ 30).

RESULTS

Of the 1236 women, 354 (28.6%) were overweight and 206 (16.7%) were obese at the start of pregnancy follow-up. Mean age at this time was 33 years (SD 6). Risk factors for a cesarean-section delivery assessed through logistic regression were maternal age (OR 1.05 95% CI 2.06-6.15; p < 0.001) and previous C-section (OR 4.21 95% CI 2.89-6.14; p < 0.001) regardless of BMI. In a propensity score analysis, pregnancy weight gain was found lower in obese vs normoweight (- 2.73 kg 95% CI - 3.74 to - 1.72 p < 0.001), and newborn weight higher in obese vs normoweight women (161.21 g 95% CI 57.94-264.48 p = 0.002). Labor duration and weight gain were reduced in overweight vs normoweight subjects (- 0.72 h 95% CI - 1.27 to - 0.17 p = 0.010 and 0.81 kg 95% CI - 1.50 to - 0.12 p = 0.021, respectively).

CONCLUSIONS

In this cohort, obese women showed higher rates of prenatal complications yet obesity and overweight were not related to worse puerperium outcomes.

摘要

目的

比较连续队列中孕妇的基础 BMI 与妊娠、分娩和早期产褥期母婴并发症的发生率。

方法

本回顾性队列研究比较了 1236 名孕妇的妊娠结局指标,这些孕妇的体重指数(BMI)在 2017 年 1 月至 2018 年 5 月期间进行管理。数据收集了个人史(吸烟、糖尿病和高血压)、产科和 BMI(kg/m)(正常体重 18.5-24.9、超重 25-29.9、肥胖≥30)。

结果

在 1236 名女性中,354 名(28.6%)在妊娠随访开始时超重,206 名(16.7%)肥胖。此时的平均年龄为 33 岁(标准差 6 岁)。通过逻辑回归评估的剖宫产分娩风险因素是产妇年龄(OR 1.05 95%CI 2.06-6.15;p<0.001)和既往剖宫产(OR 4.21 95%CI 2.89-6.14;p<0.001),而与 BMI 无关。在倾向评分分析中,与正常体重相比,肥胖患者的妊娠体重增加较少(-2.73 公斤 95%CI-3.74 至-1.72,p<0.001),而肥胖患者的新生儿体重较高(161.21 克 95%CI 57.94-264.48,p=0.002)。与正常体重相比,超重患者的分娩时间和体重增加减少(-0.72 小时 95%CI-1.27 至-0.17,p=0.010 和 0.81 公斤 95%CI-1.50 至-0.12,p=0.021)。

结论

在本队列中,肥胖女性产前并发症发生率较高,但肥胖和超重与不良产褥期结局无关。

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