School of Medicine-Greenville, University of South Carolina, USA.
Department of Surgery, Greenville Memorial Hospital, Prisma Health Upstate, USA.
Am Surg. 2021 Sep;87(9):1452-1456. doi: 10.1177/0003134820954824. Epub 2021 Apr 8.
Obesity is an epidemic in the United States, known to be associated with comorbidities. However, some data show that obesity may be a protective factor in some instances. The purpose of this study is to determine if there are differences in morbidity and mortality when comparing the obese and non-obese critically ill trauma patient populations.
This was a retrospective study conducted at Prisma Health Upstate in Greenville, South Carolina, an Adult Level 1 Trauma Center. Patients over the age of 18 years admitted due to trauma from February 6, 2016 to February 28, 2019 were included in this study. Burn patients were excluded. An online trauma database was used to obtain age, sex, body mass index, Glasgow coma score (GCS), injury severity score (ISS), revised trauma score (RTS), days on mechanical ventilation, hospital length of stay (LOS), and intensive care unit (ICU) LOS.
There were 2365 critically ill trauma patients who met inclusion criteria for this study. 1570 patients were men (66.38%) and mean age was 53.2 ± 20.9. Of the patients, 2166 patients had blunt trauma (91.59%). Median GCS was 15 (interquartilerange [IQR]: 12, 15), median RTS was 12 (IQR: 11, 12), and median ISS was 17 (IQR: 9, 22). Obese critically ill trauma patients had significantly lower odds of mortality than nonobese (OR .686, CI 0.473-.977). Penetrating traumas (OR: 4.206, CI: 2.478, 6.990), increased ISS (OR: 1.095, CI: .473, 1.112), and increased age (OR: 1.036, CI: 1.038, 1.045) were associated with significantly increased odds of mortality.
The obesity paradox is observed in the obese critically ill trauma patient population.
肥胖是美国的一种流行病,已知与合并症有关。然而,一些数据表明,在某些情况下,肥胖可能是一种保护因素。本研究的目的是确定比较肥胖和非肥胖危重症创伤患者人群时发病率和死亡率是否存在差异。
这是一项在南卡罗来纳州格林维尔的普莱姆健康乌普萨拉进行的回顾性研究,这是一家成人一级创伤中心。本研究纳入了 2016 年 2 月 6 日至 2019 年 2 月 28 日因创伤入院且年龄超过 18 岁的患者。排除烧伤患者。使用在线创伤数据库获取年龄、性别、体重指数、格拉斯哥昏迷评分(GCS)、损伤严重程度评分(ISS)、修订创伤评分(RTS)、机械通气天数、住院时间(LOS)和重症监护病房(ICU) LOS。
共有 2365 名符合本研究纳入标准的危重症创伤患者。1570 名男性(66.38%),平均年龄 53.2 ± 20.9 岁。患者中,2166 名患者为钝器伤(91.59%)。中位 GCS 为 15(四分位距[IQR]:12,15),中位 RTS 为 12(IQR:11,12),中位 ISS 为 17(IQR:9,22)。肥胖危重症创伤患者的死亡率明显低于非肥胖患者(OR.686,CI 0.473-.977)。穿透性创伤(OR:4.206,CI:2.478,6.990)、ISS 增加(OR:1.095,CI:.473,1.112)和年龄增加(OR:1.036,CI:1.038,1.045)与死亡率显著增加相关。
肥胖危重症创伤患者人群中存在肥胖悖论。