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胰腺癌放射治疗中的争议

Controversies in radiotherapy for pancreas cancer.

作者信息

Nehlsen Anthony D, Goodman Karyn A

机构信息

Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, USA.

出版信息

J Surg Oncol. 2021 May;123(6):1460-1466. doi: 10.1002/jso.26313.

Abstract

The management of pancreatic adenocarcinoma remains an area of controversy and ongoing discovery. Despite advances in surgical and radiation techniques, as well as chemotherapeutic agents, outcomes of patients diagnosed with this devastating malignancy remain poor. This article aims to review the available literature evaluating the efficacy of adjuvant, neoadjuvant, and definitive radiation therapy. We will also highlight areas of ongoing research efforts being carried out to improve outcomes in this patient population.

摘要

胰腺腺癌的治疗仍然是一个存在争议且不断探索的领域。尽管手术、放疗技术以及化疗药物都取得了进展,但被诊断患有这种毁灭性恶性肿瘤的患者的预后仍然很差。本文旨在综述评估辅助放疗、新辅助放疗和根治性放疗疗效的现有文献。我们还将重点介绍为改善该患者群体的预后而正在进行的研究领域。

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