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胰腺癌放射治疗中的争议

Controversies in radiotherapy for pancreas cancer.

作者信息

Nehlsen Anthony D, Goodman Karyn A

机构信息

Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, USA.

出版信息

J Surg Oncol. 2021 May;123(6):1460-1466. doi: 10.1002/jso.26313.

DOI:10.1002/jso.26313
PMID:33831248
Abstract

The management of pancreatic adenocarcinoma remains an area of controversy and ongoing discovery. Despite advances in surgical and radiation techniques, as well as chemotherapeutic agents, outcomes of patients diagnosed with this devastating malignancy remain poor. This article aims to review the available literature evaluating the efficacy of adjuvant, neoadjuvant, and definitive radiation therapy. We will also highlight areas of ongoing research efforts being carried out to improve outcomes in this patient population.

摘要

胰腺腺癌的治疗仍然是一个存在争议且不断探索的领域。尽管手术、放疗技术以及化疗药物都取得了进展,但被诊断患有这种毁灭性恶性肿瘤的患者的预后仍然很差。本文旨在综述评估辅助放疗、新辅助放疗和根治性放疗疗效的现有文献。我们还将重点介绍为改善该患者群体的预后而正在进行的研究领域。

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1
Controversies in radiotherapy for pancreas cancer.胰腺癌放射治疗中的争议
J Surg Oncol. 2021 May;123(6):1460-1466. doi: 10.1002/jso.26313.
2
Indications for Radiation in Pancreatic Adenocarcinoma: A Review.胰腺癌放疗适应证:综述。
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Acta Biomed. 2003;74 Suppl 2:91-5.
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Radiotherapy in the adjuvant management of pancreatic adenocarcinoma: is it helpful?胰腺癌辅助治疗中的放射治疗:是否有帮助?
Expert Rev Gastroenterol Hepatol. 2012 Apr;6(2):149-61. doi: 10.1586/egh.12.3.
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Radiation therapy in the management of pancreatic adenocarcinoma: review of current evidence and future opportunities.放射治疗在胰腺腺癌治疗中的应用:当前证据综述与未来机遇
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Adjuvant therapy for pancreatic cancer: to treat or not to treat?胰腺癌的辅助治疗:治疗还是不治疗?
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Perioperative outcomes and survival following neoadjuvant stereotactic body radiation therapy (SBRT) versus intensity-modulated radiation therapy (IMRT) in pancreatic adenocarcinoma.胰腺癌新辅助立体定向体部放射治疗(SBRT)与调强放射治疗(IMRT)后的围手术期结局和生存率
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Evolving concepts regarding the use of radiotherapy in the adjuvant management of periampullary pancreatic adenocarcinoma.关于在胰头十二指肠周围腺癌辅助治疗中应用放疗的概念的演变。
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Preoperative chemoradiation therapy for adenocarcinoma of the pancreas: The Fox Chase Cancer Center experience, 1986-2003.胰腺腺癌的术前放化疗:福克斯蔡斯癌症中心的经验,1986 - 2003年
Surg Oncol Clin N Am. 2004 Oct;13(4):685-96, x. doi: 10.1016/j.soc.2004.06.013.
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Radiotherapy in the adjuvant management of pancreatic adenocarcinoma.胰腺癌辅助治疗中的放射疗法。
Semin Oncol. 2005 Dec;32(6 Suppl 9):S30-2. doi: 10.1053/j.seminoncol.2005.04.015.

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The Clinical Diagnostic Value of F-FDG PET/CT Combined with MRI in Pancreatic Cancer.F-FDG PET/CT 联合 MRI 对胰腺癌的临床诊断价值。
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