短讯：默克尔细胞癌病例中的7号染色体长臂缺失、6号和11号染色体三体性
Short communication: deletion 7q, trisomy 6 and 11 in a case of Merkel-cell carcinoma.
作者信息
Sandbrink F, Müller L, Fiebig H H, Kovacs G
机构信息
Institute of Pathology, Hannover Medical School, Federal Republic of Germany.
出版信息
Cancer Genet Cytogenet. 1988 Jul 15;33(2):305-9. doi: 10.1016/0165-4608(88)90039-8.
PMID:3383171
Abstract
Chromosome analysis of a metastatic Merkel-cell carcinoma established as xenografted tumor line in nude mice was performed. The analyzed karyotypes showed a stable cytogenetic feature characterized by trisomy 6 and 11 and a partial deletion of the long arm of chromosome #7 with the breakpoint localized at q31.2.
摘要
对在裸鼠中建立为异种移植肿瘤系的转移性默克尔细胞癌进行了染色体分析。分析的核型显示出一种稳定的细胞遗传学特征，其特点是6号和11号染色体三体以及7号染色体长臂部分缺失，断点位于q31.2。
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