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整脊手法医学治疗与脑震荡后综合征相关的头痛。

Osteopathic manipulative medicine in the management of headaches associated with postconcussion syndrome.

机构信息

Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.

Department of Physical Medicine and Rehabilitation, Hackensack Meridian Health, Shore Rehabilitation Institute, Brick Township, NJ, USA.

出版信息

J Osteopath Med. 2021 Apr 9;121(7):651-656. doi: 10.1515/jom-2020-0035.

Abstract

CONTEXT

Previous studies have demonstrated the effectiveness of osteopathic manipulative treatment (OMT) for various headache types, with limited evidence of its use for headaches related to mild traumatic brain injury (MTBI). No studies prior studies were found regarding OMT for headaches in patients with postconcussion syndrome (PCS), defined as symptom persistence for longer than 3 months after MTBI.

OBJECTIVES

To evaluate OMT for headaches in patients with PCS.

METHODS

A controlled pilot study was conducted of patients with PCS who presented to an outpatient interdisciplinary rehabilitation clinic; patients with symptoms lasting longer than 3 months were enrolled and randomly assigned to an OMT treatment group or a control group. Primary outcome measures were immediate change in headache scores according to a Visual Analog Scale (VAS) and change in the six item Headache Impact Test (HIT-6) between baseline and follow up visits. The participants in the control group completed the HIT-6 between baseline and follow up visits but did not receive OMT and did not complete the VAS. Mean immediate VAS score change for the treatment group and mean improvement in HIT-6 scores for both groups between baseline and follow up were analyzed for statistical significance.

RESULTS

A total of 26 patients were included in this study: 13 (50%) in the treatment group and 13 (50%) in the control group. Six patients (23.1%), three from each group, did not complete the study, so 10 subjects in each group were included in the final analysis. Statistically significant improvement in VAS scores was seen immediately after OMT in the treatment group (mean change, 2.1;p=0.002). Mean HIT-6 scores showed improvement in the treatment group compared with the control group, although the change was not statistically significant (p=0.15) from baseline to follow up visit. No adverse effects from treatments were noted.

CONCLUSIONS

Patients with headaches secondary to PCS showed immediate benefit in headache pain intensity after OMT. However, no sustained benefit was found on the follow up visit compared with the control group.

摘要

背景

之前的研究已经证明了整骨疗法(OMT)对各种头痛类型的有效性,但其在轻度创伤性脑损伤(MTBI)相关头痛中的应用证据有限。没有发现关于 OMT 治疗创伤后综合征(PCS)患者头痛的研究,PCS 定义为 MTBI 后症状持续超过 3 个月。

目的

评估 OMT 治疗 PCS 患者头痛的效果。

方法

对就诊于门诊多学科康复诊所的 PCS 患者进行了一项对照性初步研究;招募了症状持续时间超过 3 个月的患者,并将其随机分配到 OMT 治疗组或对照组。主要结局指标是根据视觉模拟量表(VAS)评估头痛评分的即刻变化,以及在基线和随访时六分量表头痛影响测试(HIT-6)的变化。对照组的参与者在基线和随访时完成 HIT-6,但未接受 OMT 且未完成 VAS。分析治疗组即刻 VAS 评分的平均变化和两组之间基线和随访时 HIT-6 评分的平均改善情况,以评估统计学意义。

结果

这项研究共纳入 26 名患者:治疗组 13 名(50%),对照组 13 名(50%)。6 名患者(23.1%),每组 3 名,未完成研究,因此每组有 10 名患者纳入最终分析。治疗组在 OMT 后即刻 VAS 评分显著改善(平均变化 2.1;p=0.002)。与对照组相比,治疗组的 HIT-6 评分有所改善,尽管从基线到随访时的变化无统计学意义(p=0.15)。未观察到治疗的不良反应。

结论

PCS 继发头痛患者在接受 OMT 后头痛强度即刻获益。然而,与对照组相比,在随访时未发现持续获益。

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