Zhang W J, Liu Y, Sun X Y, Zhao S, Quan H X
Department of Stomatology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2021 Apr 9;56(4):362-369. doi: 10.3760/cma.j.cn112144-20200707-00402.
To systematically evaluate the clinical effect of anodized implants and sandblasted, large-grit, acid-etched (SLA) implants in the recent 10 years, so as to provide a reference for the selection and evaluation of implants. The data from Pubmed, Cochrane Library, Embase, CNKI, and Wanfang Data database from January 2010 to April 2020 were searched, to find clinical studies on anodized and SLA implants. According to the inclusion and exclusion criteria, literature was strictly screened, and data was extracted. Included studies were evaluated by using the methodological index for non-randomized studies (MINORS) and were analyzed by Stata14.0. The outcome of interest was cumulative survival rate (CSR) and marginal bone loss (MBL). Heterogeneity and publication bias among included literature was evaluated comprehensively. A total of 22 articles, including 6 276 anodized implants, were collected for the analysis of anodized implants. Meta-analysis of proportions showed that anodized implants CSR were 98% (95%: 97%-98%, <0.05) in total, at 5 years were 98% (95%: 98%-99%, <0.05), and at 10 years were 97% (95%: 96%-98%, <0.05). MBL change was 1.02 mm (95%: 0.69-1.34, <0.05) in total. A total of 17 articles, including 4 567 SLA implants, were collected for the analysis of SLA implants. Meta-analysis of proportions showed that SLA implants CSR were 99% (95%: 98%-100%, <0.05) in total, 99% at 5 years (95%: 98%-100%, <0.05), and 99% at 10 years (95%: 97%-100%, <0.05). MBL change was 0.69 mm (95%: 0.44-0.95, <0.05) in total. The results of the above two studies were tested for bias (>0.05), indicating no significant publication bias. Meta-analysis suggested that SLA implants have higher CSR and lower MBL than anodized implants.
为系统评价近10年阳极氧化种植体和喷砂大颗粒酸蚀（SLA）种植体的临床效果，为种植体的选择和评价提供参考。检索2010年1月至2020年4月Pubmed、Cochrane图书馆、Embase、中国知网和万方数据数据库的数据，查找关于阳极氧化种植体和SLA种植体的临床研究。根据纳入和排除标准，严格筛选文献并提取数据。采用非随机研究方法学指标（MINORS）对纳入研究进行评价，并用Stata14.0进行分析。感兴趣的结局指标为累积生存率（CSR）和边缘骨丢失（MBL）。综合评价纳入文献的异质性和发表偏倚。共收集22篇文章，其中包括6276颗阳极氧化种植体用于阳极氧化种植体分析。比例的Meta分析显示，阳极氧化种植体的总CSR为98%（95%：97%-98%，P<0.05），5年时为98%（95%：98%-99%，P<0.05），10年时为97%（95%：96%-98%，P<0.05）。MBL总变化为1.02mm（95%：0.69-1.34，P<0.05）。共收集17篇文章，其中包括4567颗SLA种植体用于SLA种植体分析。比例的Meta分析显示，SLA种植体的总CSR为99%（95%：98%-100%，P<0.05），5年时为99%（95%：98%-100%，P<0.05），10年时为99%（95%：97%-
