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新冠大流行对妊娠结局的影响。

Effects of the COVID pandemic on pregnancy outcomes.

机构信息

Fetal Medicine Unit, St George's Hospital, St George's University of London, UK.

Fetal Medicine Unit, St George's Hospital, St George's University of London, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, UK.

出版信息

Best Pract Res Clin Obstet Gynaecol. 2021 Jun;73:125-136. doi: 10.1016/j.bpobgyn.2021.03.004. Epub 2021 Mar 18.

Abstract

Pregnant women and neonates are often categorised as being at high risk during the coronavirus disease-2019 (COVID-19) pandemic. Numerous studies have demonstrated that the characteristics of COVID-19 disease in pregnant women and non-pregnant women are very similar. However, pregnant women with COVID-19 in the third trimester are more likely than their non-pregnant counterparts to require intensive care, though this may reflect a lower threshold for intervention in pregnant women rather than more serious disease. Compared with pregnant women without COVID-19, pregnant women with symptomatic COVID-19 requiring admission to hospital have worse maternal outcomes, including death, although the absolute risk remains very low. Outcomes of neonates born to women positive for COVID-19 are generally very good, though iatrogenic preterm birth is more common. Findings from these studies highlight the need for further monitoring of the outcomes of pregnant and post-partum women according to trimester during this pandemic.

摘要

孕妇和新生儿在 2019 冠状病毒病(COVID-19)大流行期间通常被归类为高危人群。许多研究表明,孕妇和非孕妇的 COVID-19 疾病特征非常相似。然而,与非孕妇相比,处于 COVID-19 第三孕期的孕妇更有可能需要重症监护,尽管这可能反映了孕妇的干预阈值较低,而不是疾病更严重。与没有 COVID-19 的孕妇相比,需要住院治疗的有症状 COVID-19 的孕妇其母体结局更差,包括死亡,尽管绝对风险仍然很低。COVID-19 阳性孕妇所生新生儿的结局通常非常好,尽管医源性早产更为常见。这些研究结果强调,在大流行期间,需要根据孕期进一步监测孕妇和产后妇女的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c922/7969862/073ea7ad8d12/gr1_lrg.jpg

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