Fetal Medicine Unit, St George's Hospital, St George's University of London, UK.
Fetal Medicine Unit, St George's Hospital, St George's University of London, UK; Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, UK.
Best Pract Res Clin Obstet Gynaecol. 2021 Jun;73:125-136. doi: 10.1016/j.bpobgyn.2021.03.004. Epub 2021 Mar 18.
Pregnant women and neonates are often categorised as being at high risk during the coronavirus disease-2019 (COVID-19) pandemic. Numerous studies have demonstrated that the characteristics of COVID-19 disease in pregnant women and non-pregnant women are very similar. However, pregnant women with COVID-19 in the third trimester are more likely than their non-pregnant counterparts to require intensive care, though this may reflect a lower threshold for intervention in pregnant women rather than more serious disease. Compared with pregnant women without COVID-19, pregnant women with symptomatic COVID-19 requiring admission to hospital have worse maternal outcomes, including death, although the absolute risk remains very low. Outcomes of neonates born to women positive for COVID-19 are generally very good, though iatrogenic preterm birth is more common. Findings from these studies highlight the need for further monitoring of the outcomes of pregnant and post-partum women according to trimester during this pandemic.
孕妇和新生儿在 2019 冠状病毒病(COVID-19)大流行期间通常被归类为高危人群。许多研究表明,孕妇和非孕妇的 COVID-19 疾病特征非常相似。然而,与非孕妇相比,处于 COVID-19 第三孕期的孕妇更有可能需要重症监护,尽管这可能反映了孕妇的干预阈值较低,而不是疾病更严重。与没有 COVID-19 的孕妇相比,需要住院治疗的有症状 COVID-19 的孕妇其母体结局更差,包括死亡,尽管绝对风险仍然很低。COVID-19 阳性孕妇所生新生儿的结局通常非常好,尽管医源性早产更为常见。这些研究结果强调,在大流行期间,需要根据孕期进一步监测孕妇和产后妇女的结局。