Department of Obstetrics and Gynecology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Department of Obstetrics and Gynecology, Kaohsiung Medical University Hospital, Kaohsiung, Medical University, Kaohsiung, Taiwan.
Int J Med Sci. 2021 Jan 1;18(3):763-767. doi: 10.7150/ijms.49923. eCollection 2021.
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is an emerging disease. There has been a rapid increase in cases and deaths since it was identified in Wuhan, China, in early December 2019, with over 4,000,000 cases of COVID-19 including at least 250,000 deaths worldwide as of May 2020. However, limited data about the clinical characteristics of pregnant women with COVID-19 have been reported. Given the maternal physiologic and immune function changes during pregnancy, pregnant women may be at a higher risk of being infected with SARS-CoV-2 and developing more complicated clinical events. Information on severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) may provide insights into the effects of COVID-19's during pregnancy. Even though SARS and MERS have been associated with miscarriage, intrauterine death, fetal growth restriction and high case fatality rates, the clinical course of COVID-19 pneumonia in pregnant women has been reported to be similar to that in non-pregnant women. In addition, pregnant women do not appear to be at a higher risk of catching COVID-19 or suffering from more severe disease than other adults of similar age. Moreover, there is currently no evidence that the virus can be transmitted to the fetus during pregnancy or during childbirth. Babies and young children are also known to only experience mild forms of COVID-19. The aims of this systematic review were to summarize the possible symptoms, treatments, and pregnancy outcomes of women infected with COVID-19 during pregnancy.
新型冠状病毒病（COVID-19）由严重急性呼吸系统综合征冠状病毒 2 型（SARS-CoV-2）引起，是一种新发疾病。自 2019 年 12 月初在中国武汉首次发现以来，COVID-19 病例和死亡人数迅速增加，截至 2020 年 5 月，全球已有超过 400 万例 COVID-19 病例，至少 25 万人死亡。然而，关于妊娠合并 COVID-19 的临床特征的有限数据已经被报道。鉴于妊娠期间孕妇的生理和免疫功能变化，孕妇感染 SARS-CoV-2 和发生更复杂的临床事件的风险可能更高。有关严重急性呼吸综合征（SARS）和中东呼吸综合征（MERS）的信息可能为了解 COVID-19 在妊娠期间的影响提供了一些见解。尽管 SARS 和 MERS 与流产、宫内死胎、胎儿生长受限和高病死率有关，但据报道，妊娠合并 COVID-19 肺炎的临床过程与非妊娠妇女相似。此外，孕妇感染 COVID-19 的风险似乎并不高于其他年龄相仿的成年人，且病情也不更严重。此外，目前尚无证据表明病毒可在妊娠期或分娩期间传播给胎儿。婴儿和幼儿也已知只经历 COVID-19 的轻度形式。本系统评价的目的是总结妊娠期感染 COVID-19 的女性可能出现的症状、治疗方法和妊娠结局。
