Williamson Sarah Louise, McDermott Helen, Gowda Harsha
Neonatal Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Neonatal Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Arch Dis Child Educ Pract Ed. 2022 Aug;107(4):298-301. doi: 10.1136/archdischild-2020-320574. Epub 2021 Apr 8.
There is increasing evidence reflected in both UK 2019 NICE and European guidelines suggesting that less invasive surfactant administration (LISA) reduces the need for mechanical ventilation and reduces the combined outcome of death or bronchopulmonary dysplasia, and is now the optimal method for surfactant delivery in spontaneously breathing babies. Despite this, uptake in England has been slow compared with Europe. This quality improvement project outlines the process of implementing LISA in a neonatal intensive care unit over a 2-year period, the barriers and challenges which were encountered, and how they were overcome.
英国2019年国家卫生与临床优化研究所（NICE）指南和欧洲指南都反映出越来越多的证据表明，微创表面活性剂给药（LISA）可减少机械通气的需求，并降低死亡或支气管肺发育不良的综合发生率，目前是对自主呼吸婴儿进行表面活性剂给药的最佳方法。尽管如此，与欧洲相比，英国对该方法的采用速度一直较慢。本质量改进项目概述了在新生儿重症监护病房两年期间实施LISA的过程、遇到的障碍和挑战，以及如何克服这些障碍。
