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三维计算机断层扫描重建与单侧完全性唇腭裂鼻端畸形的测量。

Three-Dimensional Computed Tomography Reconstruction and Measurement of Nasal End Deformity in Complete Unilateral Cleft Lip and Palate.

机构信息

From the Center for Cleft Lip and Palate Treatment, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing China.

出版信息

Ann Plast Surg. 2021 Nov 1;87(5):562-568. doi: 10.1097/SAP.0000000000002837.

Abstract

BACKGROUND

The repair of nasal deformities secondary to cleft lip and palate is complex and requires reliable preoperative nasal 3-dimensional assessment. This study explored nasal end (defined as the lower third of the external nasal and vestibular parts of the nasal cavity) deformities secondary to unilateral complete cleft lip and palate.

METHODS

Three-dimensional nasal end morphometric measurements were obtained from 48 patients who had undergone Millard cleft lip repair and reached skeletal maturity (cleft group) and from 36 age- and ethnicity-matched normal subjects (control group). For the cleft group, paired t tests and 1-way analysis of covariance were used to evaluate the internal and external morphological characteristics of the cleft and noncleft sides of the nasal end, and correlation analysis was done to evaluate the relationship between cleft-side measurements.

RESULTS

In the cleft group, the cleft side showed significantly smaller nasal vestibular volume and skin area, nostril area, nasal column length, and nostril height and greater nostril base length and nasal alar length than the noncleft side (all P < 0.05). Controlling for sex, there were significant differences in the nasal vestibular volume and skin area, internal nasal valve area, long nostril diameter, nostril base length, columella length, nostril height, and nasal alar length between the cleft and control groups (all P < 0.05). On the cleft side, the area of the skin lining of the nasal vestibule positively correlated with the alar length (r = 0.67, P < 0.05).

CONCLUSIONS

Three-dimensional nasal end reconstruction provides a more detailed preoperative nasal end morphological evaluation than previously available techniques.

LEVEL OF EVIDENCE

Level III, case-control study.

摘要

背景

唇腭裂继发鼻畸形的修复较为复杂,需要可靠的术前鼻三维评估。本研究探讨了单侧完全性唇腭裂继发的鼻端畸形。

方法

对 48 例行 Millard 唇裂修复术且达到骨骼成熟的患者(唇裂组)和 36 名年龄和种族匹配的正常受试者(对照组)的三维鼻端形态学测量值进行了分析。对于唇裂组,采用配对 t 检验和单因素协方差分析比较了鼻端裂侧和非裂侧的内部和外部形态特征,并进行相关性分析以评估裂侧测量值之间的关系。

结果

在唇裂组中,裂侧的鼻前庭容积和皮肤面积、鼻孔面积、鼻柱长度、鼻孔高度以及鼻孔基底长度和鼻翼长度均明显小于非裂侧(均 P < 0.05)。控制性别后,唇裂组和对照组在鼻前庭容积和皮肤面积、内鼻阀区面积、长鼻孔直径、鼻孔基底长度、鼻中隔长度、鼻孔高度和鼻翼长度方面仍存在显著差异(均 P < 0.05)。在裂侧,鼻前庭皮肤衬里面积与鼻翼长度呈正相关(r = 0.67,P < 0.05)。

结论

与传统技术相比,三维鼻端重建可提供更详细的术前鼻端形态评估。

证据水平

III 级,病例对照研究。

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