Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.
Department of Renal Transplant Surgery, Masuko Memorial Hospital, Nagoya, Aichi, Japan.
Ann Transplant. 2021 Apr 9;26:e929752. doi: 10.12659/AOT.929752.
BACKGROUND Hand-assisted laparoscopic donor nephrectomy (HALDN) is frequently performed in living kidney transplantation donors. This study investigated the efficacy and safety of HALDN for living donors with abdominal surgical histories. MATERIAL AND METHODS A total of 573 living kidney donors underwent donor nephrectomies for living donor kidney transplantation between January 2008 and May 2015. Eighteen donors underwent open donor nephrectomy and were excluded from analyses. Left HALDN was performed in 533 donors, including 44 donors with abdominal surgical histories and 489 donors without abdominal surgical histories. Right HALDN was performed in 22 donors, including 11 donors with abdominal surgical histories and 11 donors without abdominal surgical histories. Graft quality including the lengths of arteries, veins and ureters, time to initial urination, recipient complications, and recipient estimated glomerular filtration rate (eGFR) and operation quality including warm ischemic time, blood loss, operation duration, donor complications and donor eGFR, were compared between donors with and without abdominal surgical histories in the left and right HALDN groups. RESULTS The metrics of graft and operation quality were similar between living kidney donors with and without a history of abdominal surgery who underwent left or right HALDN. CONCLUSIONS The efficacy and safety of HALDN were not impaired by abdominal surgical histories.
手助腹腔镜供体肾切除术(HALDN)常用于活体肾移植供体。本研究调查了 HALDN 对有腹部手术史的活体供体的疗效和安全性。
2008 年 1 月至 2015 年 5 月,共有 573 名活体供体接受了活体供肾移植的供体肾切除术。18 名供体接受了开放性供体肾切除术,未纳入分析。533 名供体行左侧 HALDN,其中 44 名有腹部手术史,489 名无腹部手术史。22 名供体行右侧 HALDN,其中 11 名有腹部手术史,11 名无腹部手术史。比较了左侧和右侧 HALDN 组中有无腹部手术史的供体之间的移植物质量(包括动脉、静脉和输尿管的长度、首次排尿时间、受者并发症、受者估算肾小球滤过率(eGFR))和手术质量(包括热缺血时间、失血量、手术时间、供体并发症和供体 eGFR)。
在接受左侧或右侧 HALDN 的有或无腹部手术史的活体供体中,移植物和手术质量的指标相似。
腹部手术史并不影响 HALDN 的疗效和安全性。