Suppr超能文献

胆囊切除术在有症状的运动亢进性胆囊患者中的作用。

Role of Cholecystectomy in Symptomatic Hyperkinetic Gallbladder Patients.

作者信息

Singh Jai P

机构信息

Department of Surgery, Oswego Hospital, New York 13126, USA.

出版信息

Case Rep Surg. 2021 Mar 25;2021:5569850. doi: 10.1155/2021/5569850. eCollection 2021.

Abstract

INTRODUCTION

Biliary dyskinesia is defined by a gallbladder ejection fraction (EF) of less than 35% on HIDA scan, and these patients have shown a good response to cholecystectomy. Management of patients with biliary colic symptoms who have a hyperkinetic gallbladder (EF > 80%) is not clearly defined. Herein, I report three cases of the symptomatic hyperkinetic gallbladder that were successfully managed with cholecystectomy. Patient 1was a 56-year-old female presented with pain in the right upper abdomen for one month. Her workup was unremarkable except for the gallbladder EF of 86%. Patient 2 was a 33-year-old female with similar symptoms and workup with gallbladder EF of 97%. Patient 3 was a 20-year-old female with right upper abdominal pain and gallbladder EF of 91%. Patients 1 and 3 had the normal US, normal CT scan, and normal EGD. Patient 2 had normal US and CT but did not undergo EGD. All three patients underwent laparoscopic cholecystectomy and had complete resolution of their symptoms.

CONCLUSION

The hyperkinetic gallbladder is a rare phenomenon, which can cause debilitating right upper quadrant pain. All three patients had an excellent response to cholecystectomy. Therefore, it is concluded that the patients with biliary colic and gallbladder EF of 80% or higher should be strongly considered for surgery.

摘要

引言

胆囊运动功能障碍定义为肝胆动态显像(HIDA)扫描时胆囊排空分数(EF)低于35%,且这些患者对胆囊切除术反应良好。对于胆囊运动亢进(EF>80%)且有胆绞痛症状患者的治疗尚无明确界定。在此,我报告3例有症状的胆囊运动亢进患者经胆囊切除术成功治疗的病例。病例1为一名56岁女性,右上腹疼痛1个月。除胆囊EF为86%外,其检查无异常。病例2为一名33岁女性,有类似症状,检查发现胆囊EF为97%。病例3为一名20岁女性,有右上腹疼痛,胆囊EF为91%。病例1和病例3的超声、CT扫描及上消化道内镜检查(EGD)均正常。病例2的超声和CT正常,但未进行EGD检查。所有3例患者均接受了腹腔镜胆囊切除术,症状完全缓解。

结论

胆囊运动亢进是一种罕见现象,可导致使人衰弱的右上腹疼痛。所有3例患者对胆囊切除术反应良好。因此,得出结论,对于有胆绞痛且胆囊EF为80%或更高的患者,应强烈考虑手术治疗。

相似文献

1
Role of Cholecystectomy in Symptomatic Hyperkinetic Gallbladder Patients.
Case Rep Surg. 2021 Mar 25;2021:5569850. doi: 10.1155/2021/5569850. eCollection 2021.
2
Is hyperkinetic gallbladder an indication for cholecystectomy?
Surg Endosc. 2019 May;33(5):1613-1617. doi: 10.1007/s00464-018-6435-2. Epub 2018 Sep 12.
3
Biliary hyperkinesia: an indication for cholecystectomy?
Surg Endosc. 2021 Jul;35(7):3244-3248. doi: 10.1007/s00464-020-07757-4. Epub 2020 Jul 6.
5
The Role of Cholecystectomy in Hyperkinetic Gallbladder: A Retrospective Cohort Study in a Rural Hospital.
Cureus. 2022 Sep 30;14(9):e29778. doi: 10.7759/cureus.29778. eCollection 2022 Sep.
6
Hyperkinetic Biliary Dyskinesia: An Underrecognized Problem With Good Surgical Outcomes After Cholecystectomy.
Cureus. 2024 Jun 26;16(6):e63237. doi: 10.7759/cureus.63237. eCollection 2024 Jun.
9
Negative workup? Laparoscopic cholecystectomy Still alleviates symptoms.
Am J Surg. 2024 Apr;230:39-42. doi: 10.1016/j.amjsurg.2023.11.035. Epub 2023 Dec 1.
10
Biliary hyperkinesia, a new diagnosis or misunderstood pathophysiology of dyskinesia: A case report.
Int J Surg Case Rep. 2019;55:80-83. doi: 10.1016/j.ijscr.2019.01.011. Epub 2019 Jan 19.

引用本文的文献

1
Role of cholecystectomy in hyperkinetic biliary dyskinesia: A systematic review and meta-analysis.
Surg Open Sci. 2025 Jun 3;26:128-134. doi: 10.1016/j.sopen.2025.06.001. eCollection 2025 Jun.
2
Biliary Hyperkinesia: An Overlooked Cause of Right Upper Quadrant Pain.
Cureus. 2025 Apr 8;17(4):e81875. doi: 10.7759/cureus.81875. eCollection 2025 Apr.
3
Biliary Hyperkinesia and Its Association With Bariatric Surgery: A Case Report and Review of Management Strategies.
Cureus. 2023 Jan 23;15(1):e34119. doi: 10.7759/cureus.34119. eCollection 2023 Jan.

本文引用的文献

1
Is hyperkinetic gallbladder an indication for cholecystectomy?
Surg Endosc. 2019 May;33(5):1613-1617. doi: 10.1007/s00464-018-6435-2. Epub 2018 Sep 12.
2
Long-term efficacy of laparoscopic cholecystectomy for the treatment of biliary dyskinesia.
Am J Surg. 2014 Mar;207(3):366-70; discussion 369-70. doi: 10.1016/j.amjsurg.2013.09.012. Epub 2013 Dec 20.
4
Normokinetic biliary dyskinesia: a novel diagnosis.
Surg Endosc. 2012 Nov;26(11):3088-93. doi: 10.1007/s00464-012-2342-0. Epub 2012 May 31.
5
The cholecystokin provocation HIDA test: recreation of symptoms is superior to ejection fraction in predicting medium-term outcomes.
J Gastrointest Surg. 2011 Feb;15(2):345-9. doi: 10.1007/s11605-010-1342-4. Epub 2010 Sep 8.
6
Biliary dyskinesia.
Surg Clin North Am. 2008 Dec;88(6):1253-72, viii-ix. doi: 10.1016/j.suc.2008.07.004.
7
Evaluation of surgical outcomes and gallbladder characteristics in patients with biliary dyskinesia.
J Gastrointest Surg. 2008 Aug;12(8):1324-30. doi: 10.1007/s11605-008-0546-3. Epub 2008 Jun 10.
8
Therapeutic efficacy of laparoscopic cholecystectomy in the treatment of biliary dyskinesia.
Am J Surg. 2004 Feb;187(2):209-12. doi: 10.1016/j.amjsurg.2003.11.027.
9
The effect of cholecystectomy on plasma cholecystokinin.
Am J Gastroenterol. 2002 Sep;97(9):2189-92. doi: 10.1111/j.1572-0241.2002.05971.x.
10
Cholecystectomy is an effective treatment for biliary dyskinesia.
Am J Surg. 1999 Dec;178(6):462-5. doi: 10.1016/s0002-9610(99)00228-7.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验