Department of Otorhinolaryngology-Head and Neck Surgery, Rush University Medical Center, United States of America.
Rush Medical College, Rush University Medical Center, United States of America.
Am J Otolaryngol. 2021 Sep-Oct;42(5):103013. doi: 10.1016/j.amjoto.2021.103013. Epub 2021 Mar 30.
The current study seeks to identify the correlation between in-office spirometry data and voice-related quality of life in patients with subglottic stenosis (SGS).
Patients with SGS of any etiology were included when in-office spirometric data was available in addition to voice-related patient-reported outcomes (PROM) data in the form of the Voice Handicap Index-10 (VHI-10) and/or the Voice-Related Quality of Life (V-RQOL) survey. Overall survey scores and individual question responses were assessed for degree of correlation to spirometric data.
Twenty-nine patients were included in the final analysis. Overall mean total VHI-10 scores totaled 7.15 (SD 9.11), while mean overall V-RQOL scores totaled 78.41 (SD 16.45). Both PEF and PIF rates correlated to total scores on the VHI and V-RQOL surveys. This correlation was stronger with PIF than with PEF, and with the V-RQOL than with the VHI. Questions related to breathlessness most closely correlated with spirometric data.
Voice-related QOL is impacted in patients with SGS in a predictable way. Breathlessness while speaking may be more impactful than inability to produce speech in this population.
本研究旨在确定声门下狭窄（SGS）患者的门诊肺功能数据与与嗓音相关的生活质量之间的相关性。
纳入了具有任何病因的 SGS 患者，其门诊肺功能数据以及嗓音相关患者报告结局（PROM）数据（以嗓音障碍指数 10 分（VHI-10）和/或嗓音相关生活质量（V-RQOL）调查的形式）可用。评估了总体调查评分和个别问题的回答与肺功能数据的相关程度。
最终分析纳入了 29 名患者。VHI-10 的总体平均总分达到 7.15（SD 9.11），而 V-RQOL 的总体平均总分达到 78.41（SD 16.45）。PEF 和 PIF 率与 VHI 和 V-RQOL 调查的总分相关。PIF 的相关性强于 PEF，而 V-RQOL 的相关性强于 VHI。与呼吸困难相关的问题与肺功能数据最密切相关。
SGS 患者的嗓音相关生活质量受到了可预测的影响。在该人群中，言语时的呼吸困难比无法发声更具影响力。
