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术中超声与非可触及性浸润性乳腺癌保乳手术后的低再次切除率相关。

Intraoperative ultrasound is associated with low re-excision rates following breast conserving surgery for non-palpable invasive breast cancers.

机构信息

BC Cancer-Kelowna, Dept. of Surgical Oncology, Kelowna, BC, Canada; UBC Department of Surgery, Kelowna and Vancouver, BC, Canada.

Northern Medical Program, University of Northern British Columbia, Prince George, BC, Canada.

出版信息

Am J Surg. 2021 Jun;221(6):1164-1166. doi: 10.1016/j.amjsurg.2021.03.055. Epub 2021 Apr 2.

DOI:10.1016/j.amjsurg.2021.03.055
PMID:33840447
Abstract

BACKGROUND

Wire localized breast biopsy (WLB) is the most commonly performed procedure for the removal of non-palpable breast cancer. It is associated with patient discomfort and high re-excision rates. Intraoperative ultrasound (IOUS) is an alternative technique that may improve patient experience and have lower re-excision rates.

METHODS

A retrospective, single surgeon experience with IOUS is compared with WLB. Case matching for variables known to impact re-excision rates is performed. Fisher's exact test was performed for categorical variables, and a T-test for continuous variables.

RESULTS

28 patients underwent IOUS and WLB. Re-excision rates were the same in patients undergoing IOUS and WLB (10.7% vs 0%; p = 0.24). The calculated resection ratio was lower with IOUS than WLB (2.99 vs 3.46; p = 0.37), but did not reach statistical significance.

CONCLUSION

In selected patients, intra-operative ultrasound can be performed with a favourable re-excision rate, and comparable amounts of tissue compared to wire localized breast biopsy.

摘要

背景

经皮导丝定位乳腺活检(WLB)是最常用于切除不可触及乳腺癌的方法。它会导致患者不适和高切检率。术中超声(IOUS)是一种替代技术,它可能会改善患者的体验并降低切检率。

方法

回顾性比较了单外科医生使用 IOUS 和 WLB 的经验。对已知影响切检率的变量进行病例匹配。对于分类变量使用 Fisher 确切检验,对于连续变量使用 T 检验。

结果

28 例患者接受了 IOUS 和 WLB。IOUS 和 WLB 患者的切检率相同(10.7% vs 0%;p=0.24)。IOUS 组的切除比例低于 WLB 组(2.99 比 3.46;p=0.37),但无统计学意义。

结论

在选择的患者中,与经皮导丝定位乳腺活检相比,术中超声可实现有利的切检率和相当数量的组织切除。

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