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胰岛素依赖型糖尿病患者肺容积减小是由于结缔组织缺陷所致吗?

Are reduced lung volumes in IDDM due to defect in connective tissue?

作者信息

Bell D, Collier A, Matthews D M, Cooksey E J, McHardy G J, Clarke B F

机构信息

Department of Medicine, Royal Infirmary, Edinburgh, Scotland, United Kingdom.

出版信息

Diabetes. 1988 Jun;37(6):829-31. doi: 10.2337/diab.37.6.829.

DOI:10.2337/diab.37.6.829
PMID:3384183
Abstract

Lung volumes were measured by spirometry and helium-dilution technique in 28 young adult men with insulin-dependent diabetes mellitus (IDDM) of long duration and compared with 16 age- and height-matched adult men without diabetes. Reduced values for forced expiratory volume at 1 s, vital capacity, functional residual capacity, total lung capacity, residual volume, and single-breath carbon monoxide transfer factor were found for the IDDM patients compared to the control subjects. The results are consistent with reduced lung volumes in IDDM patients and did not correlate with the presence or absence of mild cheiroarthropathy but may relate to duration of diabetes.

摘要

通过肺量计和氦稀释技术对28名患有长期胰岛素依赖型糖尿病(IDDM)的年轻成年男性进行肺容积测量,并与16名年龄和身高匹配的无糖尿病成年男性进行比较。与对照组相比,IDDM患者的1秒用力呼气量、肺活量、功能残气量、肺总量、残气量和单次呼吸一氧化碳转移因子值降低。结果与IDDM患者肺容积减少一致,与轻度手部关节病的有无无关,但可能与糖尿病病程有关。

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