Udongwo Ndausung E, Odak Mihir, AlBayati Asseel, Zheng Min, Tang Xiaoyin
Internal Medicine, Jersey Shore University Medical Center, Neptune, USA.
Pathology and Laboratory Medicine, Jersey Shore University Medical Center, Neptune, USA.
Cureus. 2021 Mar 6;13(3):e13732. doi: 10.7759/cureus.13732.
Gout is an arthritic syndrome that causes extensive joint damage and discomfort. It is due to an elevated uric acid level in the blood which deposits in the joints. This causes an inflammatory response and joint damage. Gout typically presents as an acute monoarticular attack, resulting in hot, erythematous, swollen, and exquisitely tender joint. Tophaceous gout, which is commonly a later complication of long-standing gout, can rarely be the presenting manifestation of gout. Tophaceous gout is considered a late complication of chronic gout. As early recognition of gout can lead to prompt initiation of treatment and improvement in clinical status, a patient with an alcohol use history who presents with polyarticular swelling and tenderness should raise the suspicion of a tophaceous gout exacerbation even if the patient does not have a documented history of gout.
痛风是一种关节炎综合征,会导致广泛的关节损伤和不适。它是由于血液中尿酸水平升高并沉积在关节中所致。这会引发炎症反应和关节损伤。痛风通常表现为急性单关节发作,导致关节发热、红斑、肿胀且极其疼痛。痛风石性痛风通常是长期痛风的后期并发症,很少会是痛风的首发表现。痛风石性痛风被认为是慢性痛风的后期并发症。由于早期识别痛风可促使及时开始治疗并改善临床状况,即使患者没有痛风的记录病史,有饮酒史且出现多关节肿胀和压痛的患者也应怀疑痛风石性痛风急性发作。