Institut national de la santé et de la recherche médicale (Inserm) U1246, Tours, France.
Institut national de la santé et de la recherche médicale (Inserm) 1123, Paris, France.
Glob Health Promot. 2021 Mar;28(1_suppl):86-88. doi: 10.1177/1757975920984727.
Randomized trials are frequently used in clinical research and considered the gold standard, but they are less common in population health intervention research (PHIR). We discuss issues that are sometimes shared and sometimes distinct between PHIR and clinical research, notably the randomization unit, design, standardization of the intervention, outcome(s) and ethical issues. In the end, both PHIR and clinical research share the common aim of assessing interventions, and randomized trials should be more widely used in PHIR, provided that how they are planned and conducted is adapted to the PHIR context.
随机对照试验常用于临床研究，被视为金标准，但在人群健康干预研究（PHIR）中则较为少见。我们讨论了 PHIR 和临床研究之间有时共同、有时不同的问题，特别是随机分组单位、设计、干预标准化、结局和伦理问题。最后，PHIR 和临床研究都有评估干预措施的共同目标，只要随机试验的计划和实施适应 PHIR 背景，就应该更广泛地应用于 PHIR。
